GO term: cytoplasm Help



Ontology: Cellular Component (GO:0005737)

Definition: All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term cytoplasm (2254 genes) or to its variants containing one or more qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) cytoplasm 452
NOT: cytoplasm 1
High-throughput (download data) cytoplasm 1167
Computational (download data) cytoplasm 1629

Links to Additional Annotations:
Genes Annotated with this Term
Jump to: top | Annotation Summary


Annotation details for genes that have been directly annotated to the term cytoplasm or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

NOT: cytoplasm
     1 gene directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ESF2/YNR054C IDA: Inferred from Direct Assay
Assigned on 2005-08-15
manually curated Hoang T, et al.  (2005) Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol 25(13):5523-34 SGD

cytoplasm
     2254 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
AAH1/YNL141W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with HAMAP:MF_03145
Last Updated 2013-03-02
computational Swiss Institute of Bioinformatics (SIB) curators and GOA curators  (2006) Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
AAP1/YHR047C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
AAR2/YBL074C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
AAT2/YLR027C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ABP1/YCR088W IDA: Inferred from Direct Assay
Assigned on 2002-05-07
high-throughput Kumar A, et al.  (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ABP140/YOR239W IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ABZ1/YNR033W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ABZ2/YMR289W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACB1/YGR037C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
ACC1/YNR016C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACE2/YLR131C IDA: Inferred from Direct Assay
Assigned on 2012-12-12
high-throughput Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 SGD
ACF2/YLR144C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACH1/YBL015W IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACM1/YPL267W IDA: Inferred from Direct Assay
Assigned on 2008-08-22
manually curated Enquist-Newman M, et al.  (2008) Modulation of the Mitotic Regulatory Network by APC-Dependent Destruction of the Cdh1 Inhibitor Acm1. Mol Cell 30(4):437-46 SGD
ACO1/YLR304C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACS1/YAL054C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACS2/YLR153C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ACT1/YFL039C IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ADD37/YMR184W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADD66/YKL206C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADE1/YAR015W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
ADE12/YNL220W IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR001114
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with HAMAP:MF_03125
Last Updated 2013-03-02
computational Swiss Institute of Bioinformatics (SIB) curators and GOA curators  (2006) Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADE2/YOR128C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
ADE3/YGR204W IDA: Inferred from Direct Assay
Assigned on 2002-05-07
high-throughput Kumar A, et al.  (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD
IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADE4/YMR300C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
ADE5,7/YGL234W IDA: Inferred from Direct Assay
Assigned on 2002-05-07
high-throughput Kumar A, et al.  (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD
IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR004733
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
ADE6/YGR061C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADE8/YDR408C IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
ADH1/YOL086C IDA: Inferred from Direct Assay
Assigned on 2013-03-19
manually curated van Loon AP and Young ET  (1986) Intracellular sorting of alcohol dehydrogenase isoenzymes in yeast: a cytosolic location reflects absence of an amino-terminal targeting sequence for the mitochondrion. EMBO J 5(1):161-5 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB
ADH2/YMR303C IDA: Inferred from Direct Assay
Assigned on 2002-05-07
high-throughput Kumar A, et al.  (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD
IDA: Inferred from Direct Assay
Assigned on 2003-10-28
high-throughput Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0963
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:SL-0086
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. UniProtKB