Ontology: Cellular Component (GO:0005685)

Definition: A ribonucleoprotein complex that contains small nuclear RNA U1.

Synonyms: snRNP U1

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term U1 snRNP (18 genes) or to its variants containing one or more qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	colocalizes_with: U1 snRNP	1
	U1 snRNP	18
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term U1 snRNP or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

U1 snRNP      18 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
LUC7/YDL087C	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2002-02-19	manually curated	Fortes P, et al.  (1999) Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition. Genes Dev 13(18):2425-38	SGD
MUD1/YBR119W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
NAM8/YHR086W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
PRP39/YML046W	IDA: Inferred from Direct Assay Assigned on 2005-11-02	manually curated	Lockhart SR and Rymond BC  (1994) Commitment of yeast pre-mRNA to the splicing pathway requires a novel U1 small nuclear ribonucleoprotein polypeptide, Prp39p. Mol Cell Biol 14(6):3623-33	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
PRP40/YKL012W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
PRP42/YDR235W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
SMB1/YER029C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
SMD1/YGR074W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SMD2/YLR275W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SMD3/YLR147C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SME1/YOR159C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SMX2/YFL017W-A	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SMX3/YPR182W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-09-22	manually curated	Neubauer G, et al.  (1997) Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc Natl Acad Sci U S A 94(2):385-90	SGD
SNP1/YIL061C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
SNR19/snR19	IDA: Inferred from Direct Assay Assigned on 2002-07-15	manually curated	Kretzner L, et al.  (1987) S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA. Cell 50(4):593-602	SGD
SNU56/YDR240C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
SNU71/YGR013W	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD
YHC1/YLR298C	IDA: Inferred from Direct Assay Assigned on 2005-09-29	manually curated	Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93	SGD

colocalizes_with: U1 snRNP      1 gene directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
MER1/YNL210W	IDA: Inferred from Direct Assay Assigned on 2007-08-24	manually curated	Spingola M and Ares M Jr  (2000) A yeast intronic splicing enhancer and Nam8p are required for Mer1p-activated splicing. Mol Cell 6(2):329-38	SGD

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