GO term: DNA-directed RNA polymerase III complex 
Ontology: Cellular Component (GO:0005666)
Definition: RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Synonyms: DNA-directed RNA polymerase III activity
View Ontology:
(graph) | 
(text)
Definition: RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
Synonyms: DNA-directed RNA polymerase III activity
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
DNA-directed RNA polymerase III complex (17 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | DNA-directed RNA polymerase III complex | 17 |
| High-throughput | none | none |
| Computational (download data) | DNA-directed RNA polymerase III complex | 1 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
DNA-directed RNA polymerase III complex or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| DNA-directed RNA polymerase III complex 17 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| RET1/YOR207C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPB10/YOR210W | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2013-05-24 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| IDA: Inferred from Direct Assay Assigned on 2010-01-19 |
manually curated | Carles C, et al. (1991) Two additional common subunits, ABC10 alpha and ABC10 beta, are shared by yeast RNA polymerases. J Biol Chem 266(35):24092-6 |
SGD | |
| RPB5/YBR154C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPB8/YOR224C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC10/YHR143W-A | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2013-05-24 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| IDA: Inferred from Direct Assay Assigned on 2010-01-19 |
manually curated | Carles C, et al. (1991) Two additional common subunits, ABC10 alpha and ABC10 beta, are shared by yeast RNA polymerases. J Biol Chem 266(35):24092-6 |
SGD | |
| RPC11/YDR045C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Chedin S, et al. (1998) The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination. Genes Dev 12(24):3857-71 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD | |
| IDA: Inferred from Direct Assay Assigned on 2013-05-24 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC17/YJL011C | IDA: Inferred from Direct Assay Assigned on 2002-08-07 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2013-05-24 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC19/YNL113W | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC25/YKL144C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| RPC31/YNL151C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC34/YNR003C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC37/YKR025W | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC40/YPR110C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPC53/YDL150W | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:IPR007811 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| RPC82/YPR190C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPO26/YPR187W | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
| RPO31/YOR116C | IDA: Inferred from Direct Assay Assigned on 2010-04-30 |
manually curated | Ferri ML, et al. (2000) A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol Cell Biol 20(2):488-95 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-04-23 |
manually curated | Huet J, et al. (1985) Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes. J Biol Chem 260(28):15304-10 |
SGD | |
