Ontology: Molecular Function (GO:0005355)

Definition: Catalysis of the transfer of the hexose monosaccharide glucose from one side of the membrane to the other.

Synonyms: galactose/glucose (methylgalactoside) porter activity; glucose permease activity; lactose/glucose efflux transporter activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term glucose transmembrane transporter activity (16 genes) or to its variants containing one or more qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	glucose transmembrane transporter activity	16
	NOT: glucose transmembrane transporter activity	2
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term glucose transmembrane transporter activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

NOT: glucose transmembrane transporter activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
RGT2/YDL138W	TAS: Traceable Author Statement Assigned on 2002-12-04	manually curated	Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69	SGD
SNF3/YDL194W	TAS: Traceable Author Statement Assigned on 2002-12-04	manually curated	Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69	SGD

glucose transmembrane transporter activity      16 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
GAL2/YLR081W	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
HXT1/YHR094C	TAS: Traceable Author Statement Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT10/YFL011W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT11/YOL156W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT13/YEL069C	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT15/YDL245C	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT16/YJR158W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT17/YNR072W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT2/YMR011W	TAS: Traceable Author Statement Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
HXT3/YDR345C	TAS: Traceable Author Statement Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
HXT4/YHR092C	TAS: Traceable Author Statement Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
HXT5/YHR096C	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2011-01-10	manually curated	Bermejo C, et al.  (2010) Dynamic analysis of cytosolic glucose and ATP levels in yeast using optical sensors. Biochem J 432(2):399-406	SGD
HXT6/YDR343C	TAS: Traceable Author Statement Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
HXT7/YDR342C	IDA: Inferred from Direct Assay Assigned on 2003-05-02	manually curated	Maier A, et al.  (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2010-06-16	manually curated	Kasahara T and Kasahara M  (2010) Identification of a Key Residue Determining Substrate Affinity in the Yeast Glucose Transporter Hxt7: A TWO-DIMENSIONAL COMPREHENSIVE STUDY. J Biol Chem 285(34):26263-8	SGD
HXT8/YJL214W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD
HXT9/YJL219W	IGI: Inferred from Genetic Interaction Assigned on 2001-10-16	manually curated	Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8	SGD

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