Ontology: Molecular Function (GO:0005200)

Definition: The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term structural constituent of cytoskeleton (38 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	structural constituent of cytoskeleton	38
High-throughput	none	none
Computational (download data)	structural constituent of cytoskeleton	4

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term structural constituent of cytoskeleton or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

structural constituent of cytoskeleton      38 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ACT1/YFL039C	IDA: Inferred from Direct Assay Assigned on 2013-04-11	manually curated	Greer C and Schekman R  (1982) Actin from Saccharomyces cerevisiae. Mol Cell Biol 2(10):1270-8	SGD
ARP1/YHR129C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Kahana JA, et al.  (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell 9(7):1741-56	SGD
ARP10/YDR106W	IPI: Inferred from Physical Interaction with SGD:ARP1, SGD:JNM1, SGD:NIP100 Assigned on 2006-04-24	manually curated	Clark SW and Rose MD  (2006) Arp10p is a pointed-end-associated component of yeast dynactin. Mol Biol Cell 17(2):738-48	SGD
ASK1/YKL052C	IDA: Inferred from Direct Assay Assigned on 2002-10-08	manually curated	Cheeseman IM, et al.  (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155(7):1137-45	SGD
BBP1/YPL255W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
BIM1/YER016W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
CDC31/YOR257W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Winsor B and Schiebel E  (1997) Review: an overview of the Saccharomyces cerevisiae microtubule and microfilament cytoskeleton. Yeast 13(5):399-434	SGD
CNM67/YNL225C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
DAD1/YDR016C	IPI: Inferred from Physical Interaction Assigned on 2002-10-08	manually curated	Cheeseman IM, et al.  (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155(7):1137-45	SGD
DAD2/YKR083C	IDA: Inferred from Direct Assay Assigned on 2002-10-08	manually curated	Cheeseman IM, et al.  (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155(7):1137-45	SGD
DAM1/YGR113W	IPI: Inferred from Physical Interaction Assigned on 2002-10-08	manually curated	Cheeseman IM, et al.  (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155(7):1137-45	SGD
DUO1/YGL061C	IPI: Inferred from Physical Interaction Assigned on 2002-10-08	manually curated	Cheeseman IM, et al.  (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155(7):1137-45	SGD
FIN1/YDR130C	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	van Hemert MJ, et al.  (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3	SGD
JNM1/YMR294W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Kahana JA, et al.  (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell 9(7):1741-56	SGD
KIP1/YBL063W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
MDM1/YML104C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Hermann GJ and Shaw JM  (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303	SGD
MHP1/YJL042W	IDA: Inferred from Direct Assay Assigned on 2002-11-26	manually curated	Irminger-Finger I and Mathis N  (1998) Effect of microtubule-associated protein MHP1 on microtubule assembly and cell cycle progression in Saccharomyces cerevisiae. Cell Struct Funct 23(4):209-19	SGD
MPS2/YGL075C	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Munoz-Centeno MC, et al.  (1999) Saccharomyces cerevisiae MPS2 encodes a membrane protein localized at the spindle pole body and the nuclear envelope. Mol Biol Cell 10(7):2393-406	SGD
NUD1/YOR373W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
NUF2/YOL069W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC105/YGL093W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC110/YDR356W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Bullitt E, et al.  (1997) The yeast spindle pole body is assembled around a central crystal of Spc42p. Cell 89(7):1077-86	SGD
SPC19/YDR201W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC24/YMR117C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC25/YER018C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC29/YPL124W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Elliott S, et al.  (1999) Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication. Proc Natl Acad Sci U S A 96(11):6205-10	SGD
SPC34/YKR037C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Wigge PA, et al.  (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77	SGD
SPC42/YKL042W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Bullitt E, et al.  (1997) The yeast spindle pole body is assembled around a central crystal of Spc42p. Cell 89(7):1077-86	SGD
SPC72/YAL047C	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Chen XP, et al.  (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79	SGD
SPC97/YHR172W	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	manually curated	Bullitt E, et al.  (1997) The yeast spindle pole body is assembled around a central crystal of Spc42p. Cell 89(7):1077-86	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR015698 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro

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