Ontology: Biological Process (GO:0051666)

Definition: Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.

Synonyms: establishment and maintenance of actin cortical patch localization; actin cortical patch localisation

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term actin cortical patch localization (15 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	actin cortical patch localization	15
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term actin cortical patch localization or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

actin cortical patch localization      15 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
AFI1/YOR129C	IGI: Inferred from Genetic Interaction with SGD:ARF3, IMP: Inferred from Mutant Phenotype Assigned on 2008-04-15	manually curated	Tsai PC, et al.  (2008) Afi1p Functions as an Arf3p Polarization-specific Docking Factor for Development of Polarity. J Biol Chem 283(24):16915-27	SGD
ARF3/YOR094W	IGI: Inferred from Genetic Interaction with SGD:PFY1 Assigned on 2008-04-15	manually curated	Zakrzewska E, et al.  (2003) A role for GEA1 and GEA2 in the organization of the actin cytoskeleton in Saccharomyces cerevisiae. Genetics 165(3):985-95	SGD
	IGI: Inferred from Genetic Interaction with SGD:LAS17, SGD:VRP1 Assigned on 2008-04-15	manually curated	Lambert AA, et al.  (2007) The Saccharomyces cerevisiae Arf3 protein is involved in actin cable and cortical patch formation. FEMS Yeast Res 7(6):782-95	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2008-04-15	manually curated	Tsai PC, et al.  (2008) Afi1p Functions as an Arf3p Polarization-specific Docking Factor for Development of Polarity. J Biol Chem 283(24):16915-27	SGD
BSP1/YPR171W	IMP: Inferred from Mutant Phenotype Assigned on 2006-03-15	manually curated	Wicky S, et al.  (2003) Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast. FEBS Lett 537(1-3):35-41	SGD
CDC50/YCR094W	IGI: Inferred from Genetic Interaction with SGD:ERG3 Assigned on 2005-12-08	manually curated	Kishimoto T, et al.  (2005) Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast. Mol Biol Cell 16(12):5592-609	SGD
CRN1/YLR429W	IMP: Inferred from Mutant Phenotype Assigned on 2008-02-29	manually curated	Galletta BJ, et al.  (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol 6(1):e1	SGD
LAS17/YOR181W	IGI: Inferred from Genetic Interaction with SGD:MYO3, SGD:MYO5, IMP: Inferred from Mutant Phenotype Assigned on 2008-02-29	manually curated	Galletta BJ, et al.  (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol 6(1):e1	SGD
LSB3/YFR024C-A	IGI: Inferred from Genetic Interaction with SGD:YSC84, IMP: Inferred from Mutant Phenotype Assigned on 2009-02-10	manually curated	Robertson AS, et al.  (2009) The WASP homologue Las17 activates the novel actin-regulatory activity of Ysc84 to promote endocytosis in yeast. Mol Biol Cell 20(6):1618-28	SGD
LSB5/YCL034W	IGI: Inferred from Genetic Interaction with SGD:YSC84 Assigned on 2009-09-25	manually curated	Dewar H, et al.  (2002) Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae. Mol Biol Cell 13(10):3646-61	SGD
MYO3/YKL129C	IGI: Inferred from Genetic Interaction with SGD:MYO5, SGD:LAS17 Assigned on 2008-02-29	manually curated	Galletta BJ, et al.  (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol 6(1):e1	SGD
MYO5/YMR109W	IGI: Inferred from Genetic Interaction with SGD:LAS17, SGD:MYO3, IMP: Inferred from Mutant Phenotype Assigned on 2008-02-29	manually curated	Galletta BJ, et al.  (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol 6(1):e1	SGD
RVS161/YCR009C	IMP: Inferred from Mutant Phenotype Assigned on 2009-03-11	manually curated	Munn AL, et al.  (1995) end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae. Mol Biol Cell 6(12):1721-42	SGD
RVS167/YDR388W	IMP: Inferred from Mutant Phenotype Assigned on 2009-03-11	manually curated	Munn AL, et al.  (1995) end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae. Mol Biol Cell 6(12):1721-42	SGD
VRP1/YLR337C	IMP: Inferred from Mutant Phenotype Assigned on 2009-03-11	manually curated	Munn AL, et al.  (1995) end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae. Mol Biol Cell 6(12):1721-42	SGD
YEL1/YBL060W	IMP: Inferred from Mutant Phenotype Assigned on 2008-04-15	manually curated	Tsai PC, et al.  (2008) Afi1p Functions as an Arf3p Polarization-specific Docking Factor for Development of Polarity. J Biol Chem 283(24):16915-27	SGD
YSC84/YHR016C	IGI: Inferred from Genetic Interaction with SGD:LSB3, IMP: Inferred from Mutant Phenotype Assigned on 2009-02-10	manually curated	Robertson AS, et al.  (2009) The WASP homologue Las17 activates the novel actin-regulatory activity of Ysc84 to promote endocytosis in yeast. Mol Biol Cell 20(6):1618-28	SGD

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