Ontology: Biological Process (GO:0000501)

Definition: The non-sexual aggregation of cells mediated by protein (flocculin)-carbohydrate interaction present in the cell wall. This process is pH- and calcium-dependent and reversible. An example of this process is found in Saccharomyces cerevisiae.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term flocculation via cell wall protein-carbohydrate interaction (4 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	flocculation via cell wall protein-carbohydrate interaction	4
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term flocculation via cell wall protein-carbohydrate interaction or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

flocculation via cell wall protein-carbohydrate interaction      4 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
FLO1/YAR050W	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-01	manually curated	Guo B, et al.  (2000) A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Proc Natl Acad Sci U S A 97(22):12158-63	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2002-11-25	manually curated	Bidard F, et al.  (1995) The Saccharomyces cerevisiae FLO1 flocculation gene encodes for a cell surface protein. Yeast 11(9):809-22	SGD
FLO10/YKR102W	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-01	manually curated	Guo B, et al.  (2000) A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Proc Natl Acad Sci U S A 97(22):12158-63	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-01	manually curated	Van Mulders SE, et al.  (2009) Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. FEMS Yeast Res 9(2):178-90	SGD
FLO5/YHR211W	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-01	manually curated	Van Mulders SE, et al.  (2009) Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. FEMS Yeast Res 9(2):178-90	SGD
	IGI: Inferred from Genetic Interaction Assigned on 2002-12-19	manually curated	Bidard F, et al.  (1994) Cloning and analysis of a FLO5 flocculation gene from S. cerevisiae. Curr Genet 25(3):196-201	SGD
FLO9/YAL063C	IEP: Inferred from Expression Pattern, ISS: Inferred from Sequence or structural Similarity with SGD:FLO1 Assigned on 2004-02-04	manually curated	Teunissen AW and Steensma HY  (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11(11):1001-13	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-01	manually curated	Van Mulders SE, et al.  (2009) Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. FEMS Yeast Res 9(2):178-90	SGD

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