Ontology: Molecular Function (GO:0004805)

Definition: Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.

Synonyms: trehalose 6-phosphate phosphatase activity; trehalose phosphatase activity; trehalose 6-phosphatase activity; trehalose-6-phosphate phosphohydrolase activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term trehalose-phosphatase activity (1 gene) or to its variants containing one or more qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	contributes_to: trehalose-phosphatase activity	2
	trehalose-phosphatase activity	1
High-throughput	none	none
Computational (download data)	trehalose-phosphatase activity	1

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term trehalose-phosphatase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

contributes_to: trehalose-phosphatase activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
TPS3/YMR261C	IGI: Inferred from Genetic Interaction with SGD:TSL1 Assigned on 2005-07-29	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD
TSL1/YML100W	IGI: Inferred from Genetic Interaction with SGD:TPS3 Assigned on 2005-07-29	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD

trehalose-phosphatase activity      1 gene directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
TPS2/YDR074W	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	De Virgilio C, et al.  (1993) Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity. Eur J Biochem 212(2):315-23	SGD
	IEA: Inferred from Electronic Annotation with IUBMB:3.1.3.12 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB

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