Ontology: Biological Process (GO:0000462)

Definition: Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

Synonyms: maturation of 18S rRNA

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (63 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	63
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)      63 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
BUD21/YOR078W	IMP: Inferred from Mutant Phenotype Assigned on 2007-09-17	manually curated	Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70	SGD
DHR2/YKL078W	IMP: Inferred from Mutant Phenotype Assigned on 2009-05-13	manually curated	Granneman S, et al.  (2006) Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol 26(4):1183-94	SGD
DIP2/YLR129W	IMP: Inferred from Mutant Phenotype Assigned on 2007-09-17	manually curated	Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70	SGD
ECM16/YMR128W	IMP: Inferred from Mutant Phenotype Assigned on 2009-05-13	manually curated	Granneman S, et al.  (2006) Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol 26(4):1183-94	SGD
EFG1/YGR271C-A	IMP: Inferred from Mutant Phenotype Assigned on 2008-06-18	manually curated	Peng WT, et al.  (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33	SGD
FAF1/YIL019W	IMP: Inferred from Mutant Phenotype Assigned on 2004-07-09	manually curated	Karkusiewicz I, et al.  (2004) Functional and physical interactions of Faf1p, a Saccharomyces cerevisiae nucleolar protein. Biochem Biophys Res Commun 319(2):349-57	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2004-07-09	manually curated	Shirai C, et al.  (2004) Ebp2p, the yeast homolog of Epstein-Barr virus nuclear antigen 1-binding protein 2, interacts with factors of both the 60 S and the 40 s ribosomal subunit assembly. J Biol Chem 279(24):25353-8	SGD
FAL1/YDR021W	IMP: Inferred from Mutant Phenotype Assigned on 2009-05-13	manually curated	Granneman S, et al.  (2006) Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol 26(4):1183-94	SGD
FAP7/YDL166C	IMP: Inferred from Mutant Phenotype Assigned on 2003-08-05	manually curated	Peng WT, et al.  (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33	SGD
	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2006-03-01	manually curated	Granneman S, et al.  (2005) The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Mol Cell Biol 25(23):10352-64	SGD
FUN12/YAL035W	IMP: Inferred from Mutant Phenotype Assigned on 2012-12-18	manually curated	Lebaron S, et al.  (2012) Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits. Nat Struct Mol Biol 19(8):744-53	SGD
FYV7/YLR068W	IMP: Inferred from Mutant Phenotype Assigned on 2003-08-04	manually curated	Peng WT, et al.  (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33	SGD
HCR1/YLR192C	IMP: Inferred from Mutant Phenotype Assigned on 2003-10-21	manually curated	Valasek L, et al.  (2001) Dual function of eIF3j/Hcr1p in processing 20 S pre-rRNA and translation initiation. J Biol Chem 276(46):43351-60	SGD
HRA1	NAS: Non-traceable Author Statement Assigned on 2006-10-27	manually curated	Samanta MP, et al.  (2006) Global identification of noncoding RNAs in Saccharomyces cerevisiae by modulating an essential RNA processing pathway. Proc Natl Acad Sci U S A 103(11):4192-7	SGD
NAN1/YPL126W	IMP: Inferred from Mutant Phenotype Assigned on 2007-09-17	manually curated	Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70	SGD
NOB1/YOR056C	IEP: Inferred from Expression Pattern, IMP: Inferred from Mutant Phenotype Assigned on 2004-11-15	manually curated	Fatica A, et al.  (2003) Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol Cell Biol 23(5):1798-807	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2005-05-11	manually curated	Fatica A, et al.  (2004) PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA. RNA 10(11):1698-701	SGD
NOP14/YDL148C	IMP: Inferred from Mutant Phenotype Assigned on 2007-09-17	manually curated	Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70	SGD
NOP19/YGR251W	IMP: Inferred from Mutant Phenotype Assigned on 2008-06-18	manually curated	Peng WT, et al.  (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33	SGD
NOP7/YGR103W	IMP: Inferred from Mutant Phenotype Assigned on 2003-08-05	manually curated	Peng WT, et al.  (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33	SGD
PRP43/YGL120C	IMP: Inferred from Mutant Phenotype Assigned on 2006-10-27	manually curated	Leeds NB, et al.  (2006) The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol 26(2):513-22	SGD
PWP2/YCR057C	IMP: Inferred from Mutant Phenotype Assigned on 2007-09-17	manually curated	Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70	SGD
RIO1/YOR119C	IDA: Inferred from Direct Assay Assigned on 2002-03-12	manually curated	Vanrobays E, et al.  (2001) Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein. EMBO J 20(15):4204-13	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-03-22	manually curated	Vanrobays E, et al.  (2003) Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. Mol Cell Biol 23(6):2083-95	SGD
RIO2/YNL207W	IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity with SGD:RIO1 Assigned on 2003-03-25	manually curated	Vanrobays E, et al.  (2003) Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. Mol Cell Biol 23(6):2083-95	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2005-03-22	manually curated	Geerlings TH, et al.  (2003) Rio2p, an evolutionarily conserved, low abundant protein kinase essential for processing of 20 S Pre-rRNA in Saccharomyces cerevisiae. J Biol Chem 278(25):22537-45	SGD
RPS11A/YDR025W	IGI: Inferred from Genetic Interaction with SGD:RPS11B Assigned on 2008-09-22	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS11B/YBR048W	IGI: Inferred from Genetic Interaction with SGD:RPS11A Assigned on 2008-09-22	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS13/YDR064W	IMP: Inferred from Mutant Phenotype Assigned on 2008-09-25	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS14A/YCR031C	IMP: Inferred from Mutant Phenotype Assigned on 2005-04-07	manually curated	Jakovljevic J, et al.  (2004) The carboxy-terminal extension of yeast ribosomal protein S14 is necessary for maturation of 43S preribosomes. Mol Cell 14(3):331-42	SGD
	IGI: Inferred from Genetic Interaction with SGD:RPS14B Assigned on 2008-09-25	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS14B/YJL191W	IMP: Inferred from Mutant Phenotype Assigned on 2005-04-07	manually curated	Jakovljevic J, et al.  (2004) The carboxy-terminal extension of yeast ribosomal protein S14 is necessary for maturation of 43S preribosomes. Mol Cell 14(3):331-42	SGD
	IGI: Inferred from Genetic Interaction with SGD:RPS14A Assigned on 2008-10-14	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS16A/YMR143W	IGI: Inferred from Genetic Interaction with SGD:RPS16B Assigned on 2008-10-14	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS16B/YDL083C	IGI: Inferred from Genetic Interaction with SGD:RPS16A Assigned on 2008-10-14	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS1A/YLR441C	IGI: Inferred from Genetic Interaction with SGD:RPS1B Assigned on 2008-12-03	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD
RPS1B/YML063W	IGI: Inferred from Genetic Interaction with SGD:RPS1A Assigned on 2008-12-03	manually curated	Ferreira-Cerca S, et al.  (2005) Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell 20(2):263-75	SGD

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