GO term: nuclease activity 
Ontology: Molecular Function (GO:0004518)
Definition: Catalysis of the hydrolysis of ester linkages within nucleic acids.
View Ontology:
(graph) | 
(text)
Definition: Catalysis of the hydrolysis of ester linkages within nucleic acids.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
nuclease activity (108 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | nuclease activity | 3 |
| High-throughput | none | none |
| Computational (download data) | nuclease activity | 107 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
nuclease activity or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| nuclease activity 108 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AI3/Q0060 | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AI4/Q0065 | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AI5_ALPHA/Q0070 | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AI5_BETA/Q0075 | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| APN2/YBL019W | IEA: Inferred from Electronic Annotation with EBI:IPR004808 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| BI2/Q0110 | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Szczepanek T and Lazowska J (1996) Replacement of two non-adjacent amino acids in the S.cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing-endonuclease activity. EMBO J 15(14):3758-67 |
SGD |
| CCE1/YKL011C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CCR4/YAL021C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DIN7/YDR263C | ISS: Inferred from Sequence or structural Similarity Assigned on 2001-01-18 |
manually curated | Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR006084, EBI:IPR006085, EBI:IPR006086 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| DIS3/YOL021C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DNA2/YHR164C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DOM34/YNL001W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DSS1/YMR287C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| EXO1/YOR033C | IEA: Inferred from Electronic Annotation with EBI:IPR006084, EBI:IPR006085, EBI:IPR006086 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0267, EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| EXO5/YBR163W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| HO/YDL227C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| LCL3/YGL085W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MKT1/YNL085W | ISS: Inferred from Sequence or structural Similarity Assigned on 2004-09-03 |
manually curated | Tadauchi T, et al. (2004) Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex. Mol Cell Biol 24(9):3670-81 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR006085, EBI:IPR006086 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| MMS4/YBR098W | IEA: Inferred from Electronic Annotation with EBI:IPR006166 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| MRE11/YMR224C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MUS81/YDR386W | IEA: Inferred from Electronic Annotation with EBI:IPR006166, EBI:IPR020819 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| NGL1/YOL042W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| NGL2/YMR285C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| NGL3/YML118W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| NOB1/YOR056C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| NUC1/YJL208C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| PAN2/YGL094C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| POL3/YDL102W | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| POP2/YNR052C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| PSO2/YMR137C | IEA: Inferred from Electronic Annotation with EBI:KW-0540 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
