Ontology: Biological Process (GO:0042991)

Definition: The directed movement of a transcription factor from the cytoplasm to the nucleus.

Synonyms: transcription factor transport from cytoplasm to nucleus; transcription factor-nucleus import; transcription factor import into cell nucleus

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term transcription factor import into nucleus (6 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	transcription factor import into nucleus	6
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term transcription factor import into nucleus or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

transcription factor import into nucleus      6 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
CMD1/YBR109C	IMP: Inferred from Mutant Phenotype Assigned on 2008-10-17	manually curated	Hanover JA, et al.  (2007) The High Mobility Group Box Transcription Factor Nhp6Ap Enters the Nucleus by a Calmodulin-dependent, Ran-independent Pathway. J Biol Chem 282(46):33743-51	SGD
KAP104/YBR017C	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction with SGD:TFG2 Assigned on 2009-04-28	manually curated	Suel KE and Chook YM  (2009) Kap104p Imports the PY-NLS-containing Transcription Factor Tfg2p into the Nucleus. J Biol Chem 284(23):15416-24	SGD
KAP114/YGL241W	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction with SGD:SUA7 Assigned on 2010-10-19	manually curated	Hodges JL, et al.  (2005) Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 16(7):3200-10	SGD
KAP120/YPL125W	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction with SGD:SWI6 Assigned on 2010-11-29	manually curated	Kim KY, et al.  (2010) Yeast Mpk1 cell wall integrity mitogen-activated protein kinase regulates nucleocytoplasmic shuttling of the Swi6 transcriptional regulator. Mol Biol Cell 21(9):1609-19	SGD
RTG2/YGL252C	IMP: Inferred from Mutant Phenotype Assigned on 2011-12-15	manually curated	Komeili A, et al.  (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2011-12-15	manually curated	Sekito T, et al.  (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15	SGD
RTG3/YBL103C	IMP: Inferred from Mutant Phenotype Assigned on 2011-12-15	manually curated	Komeili A, et al.  (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78	SGD

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