GO term: ribosomal small subunit biogenesis 
Ontology: Biological Process (GO:0042274)
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
Synonyms: ribosomal small subunit biogenesis and assembly
View Ontology:
(graph) | 
(text)
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
Synonyms: ribosomal small subunit biogenesis and assembly
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
ribosomal small subunit biogenesis (30 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | ribosomal small subunit biogenesis | 24 |
| High-throughput | none | none |
| Computational (download data) | ribosomal small subunit biogenesis | 6 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
ribosomal small subunit biogenesis or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| ribosomal small subunit biogenesis 30 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| BUD22/YMR014W | IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2010-11-08 |
manually curated | Dakshinamurthy A, et al. (2010) BUD22 Affects Ty1 Retrotransposition and Ribosome Biogenesis in Saccharomyces cerevisiae. Genetics 185(4):1193-205 |
SGD | |
| EMG1/YLR186W | IMP: Inferred from Mutant Phenotype Assigned on 2002-12-09 |
manually curated | Liu PC and Thiele DJ (2001) Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis. Mol Biol Cell 12(11):3644-57 |
SGD |
| IGI: Inferred from Genetic Interaction with SGD:RPS19B Assigned on 2012-09-19 |
manually curated | Buchhaupt M, et al. (2006) Genetic evidence for 18S rRNA binding and an Rps19p assembly function of yeast nucleolar protein Nep1p. Mol Genet Genomics 276(3):273-84 |
SGD | |
| ENP2/YGR145W | IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| HRR25/YPL204W | IMP: Inferred from Mutant Phenotype Assigned on 2006-11-29 |
manually curated | Schafer T, et al. (2006) Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature 441(7093):651-5 |
SGD |
| KRE33/YNL132W | IMP: Inferred from Mutant Phenotype Assigned on 2008-06-27 |
manually curated | Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD | |
| KRR1/YCL059C | IMP: Inferred from Mutant Phenotype Assigned on 2008-06-27 |
manually curated | Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 |
SGD |
| LTV1/YKL143W | IMP: Inferred from Mutant Phenotype Assigned on 2005-05-03 |
manually curated | Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 |
SGD |
| NEW1/YPL226W | IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| NOB1/YOR056C | IPI: Inferred from Physical Interaction Assigned on 2005-05-11 |
manually curated | Schafer T, et al. (2003) The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J 22(6):1370-80 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2007-01-19 |
manually curated | Fatica A, et al. (2003) Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol Cell Biol 23(5):1798-807 |
UniProtKB | |
| NOC4/YPR144C | IMP: Inferred from Mutant Phenotype Assigned on 2006-03-15 |
manually curated | Milkereit P, et al. (2003) A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. J Biol Chem 278(6):4072-81 |
SGD |
| NOP14/YDL148C | IMP: Inferred from Mutant Phenotype Assigned on 2006-03-15 |
manually curated | Liu PC and Thiele DJ (2001) Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis. Mol Biol Cell 12(11):3644-57 |
SGD |
| NOP6/YDL213C | IGI: Inferred from Genetic Interaction with SGD:EMG1 Assigned on 2007-04-17 |
manually curated | Buchhaupt M, et al. (2007) Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. FEMS Yeast Res 7(6):771-81 |
SGD |
| RPS19A/YOL121C | IGI: Inferred from Genetic Interaction with SGD:RPS19B, IMP: Inferred from Mutant Phenotype Assigned on 2006-06-15 |
manually curated | Leger-Silvestre I, et al. (2005) Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. J Biol Chem 280(46):38177-85 |
SGD |
| RPS19B/YNL302C | IGI: Inferred from Genetic Interaction with SGD:RPS19A, IMP: Inferred from Mutant Phenotype Assigned on 2006-06-15 |
manually curated | Leger-Silvestre I, et al. (2005) Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. J Biol Chem 280(46):38177-85 |
SGD |
| RPS21A/YKR057W | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR10442_AN0 Assigned on 2011-01-05 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RPS21B/YJL136C | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR10442_AN0 Assigned on 2011-01-05 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RPS6A/YPL090C | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR11502_AN0 Assigned on 2011-02-07 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RPS6B/YBR181C | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR11502_AN0 Assigned on 2011-02-07 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RPS7A/YOR096W | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR11278_AN0 Assigned on 2011-01-05 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RPS7B/YNL096C | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR11278_AN0 Assigned on 2011-01-05 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| RRP14/YKL082C | IMP: Inferred from Mutant Phenotype Assigned on 2007-02-08 |
manually curated | Oeffinger M, et al. (2007) Yeast Rrp14p is required for ribosomal subunit synthesis and for correct positioning of the mitotic spindle during mitosis. Nucleic Acids Res 35(4):1354-66 |
SGD |
| RRP36/YOR287C | IMP: Inferred from Mutant Phenotype Assigned on 2010-03-31 |
manually curated | Gerus M, et al. (2010) Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit. Mol Cell Biol 30(5):1130-44 |
SGD |
| SAC3/YDR159W | IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| SGD1/YLR336C | IMP: Inferred from Mutant Phenotype Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| TMA23/YMR269W | IGI: Inferred from Genetic Interaction with SGD:EMG1 Assigned on 2007-04-17 |
manually curated | Buchhaupt M, et al. (2007) Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. FEMS Yeast Res 7(6):771-81 |
SGD |
| TRM112/YNR046W | IMP: Inferred from Mutant Phenotype Assigned on 2013-05-24 |
manually curated | Sardana R and Johnson AW (2012) The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits. Mol Biol Cell 23(21):4313-22 |
SGD |
| UTP21/YLR409C | IC: Inferred By Curator from small-subunit processome Assigned on 2008-09-11 |
manually curated | Bernstein KA, et al. (2004) The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell 3(6):1619-26 |
SGD |
| UTP25/YIL091C | IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2010-05-03 |
manually curated | Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2010-06-15 |
manually curated | Goldfeder MB and Oliveira CC (2010) Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA. FEBS J 277(13):2838-52 |
SGD | |
| IMP: Inferred from Mutant Phenotype Assigned on 2010-11-04 |
manually curated | Charette JM and Baserga SJ (2010) The DEAD-box RNA helicase-like Utp25 is an SSU processome component. RNA 16(11):2156-69 |
SGD | |
| UTP30/YKR060W | IPI: Inferred from Physical Interaction with SGD:BMS1 Assigned on 2012-02-08 |
manually curated | Perez-Fernandez J, et al. (2011) Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes. Nucleic Acids Res 39(18):8105-21 |
SGD |
| YAR1/YPL239W | IGI: Inferred from Genetic Interaction with SGD:RPS3, IMP: Inferred from Mutant Phenotype Assigned on 2005-05-03 |
manually curated | Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 |
SGD |
