Ontology: Biological Process (GO:0042256)

Definition: The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mature ribosome assembly (4 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	mature ribosome assembly	3
High-throughput	none	none
Computational (download data)	mature ribosome assembly	1

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mature ribosome assembly or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mature ribosome assembly      4 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
RIA1/YNL163C	IMP: Inferred from Mutant Phenotype Assigned on 2012-02-29	manually curated	Senger B, et al.  (2001) The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis. Mol Cell 8(6):1363-73	SGD
	ISO: Inferred from Sequence Orthology with EBI:Q7Z2Z2 Assigned on 2012-02-29	manually curated	Finch AJ, et al.  (2011) Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 25(9):917-29	SGD
SDO1/YLR022C	IMP: Inferred from Mutant Phenotype Assigned on 2012-02-29	manually curated	Menne TF, et al.  (2007) The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast. Nat Genet 39(4):486-95	SGD
TIF5/YPR041W	IMP: Inferred from Mutant Phenotype Assigned on 2002-04-24	manually curated	Asano K, et al.  (2001) Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation. EMBO J 20(9):2326-37	SGD
TIF6/YPR016C	IEA: Inferred from Electronic Annotation with EBI:IPR002769 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with HAMAP:MF_03132 Last Updated 2013-03-02	computational	Swiss Institute of Bioinformatics (SIB) curators and GOA curators  (2006) Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins	UniProtKB

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