Ontology: Molecular Function (GO:0042134)

Definition: Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term rRNA primary transcript binding (5 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	rRNA primary transcript binding	5
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term rRNA primary transcript binding or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

rRNA primary transcript binding      5 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
BRX1/YOL077C	IPI: Inferred from Physical Interaction Assigned on 2003-02-19	manually curated	Wehner KA and Baserga SJ  (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39	SGD
IMP4/YNL075W	IPI: Inferred from Physical Interaction Assigned on 2003-02-19	manually curated	Wehner KA and Baserga SJ  (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39	SGD
MRD1/YPR112C	IDA: Inferred from Direct Assay Assigned on 2013-02-04	manually curated	Segerstolpe A, et al.  (2013) Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome. Nucleic Acids Res 41(2):1178-90	SGD
RPF1/YHR088W	IPI: Inferred from Physical Interaction Assigned on 2003-02-19	manually curated	Wehner KA and Baserga SJ  (2002) The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell 9(2):329-39	SGD
SNR30/snR30	IDA: Inferred from Direct Assay Assigned on 2002-11-18	manually curated	Morrissey JP and Tollervey D  (1993) Yeast snR30 is a small nucleolar RNA required for 18S rRNA synthesis. Mol Cell Biol 13(4):2469-77	SGD

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