GO term: ATP-dependent DNA helicase activity Help


Ontology: Molecular Function (GO:0004003)

Definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of the DNA helix.

Annotation Summary


This table lists the methods used to annotate genes either directly to the term ATP-dependent DNA helicase activity (16 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) ATP-dependent DNA helicase activity 4
High-throughput none none
Computational (download data) ATP-dependent DNA helicase activity 14

Links to Additional Annotations:
Genes Annotated with this Term


Annotation details for genes that have been directly annotated to the term ATP-dependent DNA helicase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

ATP-dependent DNA helicase activity
     16 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ACT1/YFL039C RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
ARP6/YLR085C RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
CHL1/YPL008W IEA: Inferred from Electronic Annotation
with EBI:IPR006554, EBI:IPR010614
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
DNA2/YHR164C IDA: Inferred from Direct Assay
Assigned on 2001-01-18
manually curated Budd ME and Campbell JL  (1995) A yeast gene required for DNA replication encodes a protein with homology to DNA helicases. Proc Natl Acad Sci U S A 92(17):7642-6 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR014808
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
HMI1/YOL095C IEA: Inferred from Electronic Annotation
with EBI:IPR000212
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
MCM2/YBL023C RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
MCM3/YEL032W RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
MCM5/YLR274W RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
RAD3/YER171W IEA: Inferred from Electronic Annotation
with EBI:IPR001945, EBI:IPR006554, EBI:IPR010614, EBI:IPR010643
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
RRM3/YHR031C IDA: Inferred from Direct Assay
Assigned on 2003-02-26
manually curated Ivessa AS, et al.  (2002) Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. Genes Dev 16(11):1383-96 SGD
SEN1/YLR430W IEA: Inferred from Electronic Annotation
with EBI:IPR000212
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
SGS1/YMR190C IDA: Inferred from Direct Assay
Assigned on 2002-08-06
manually curated Bennett RJ, et al.  (1998) Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae. J Biol Chem 273(16):9644-50 SGD
SRS2/YJL092W IEA: Inferred from Electronic Annotation
with EBI:IPR000212
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
RCA: Reviewed Computational Analysis
Assigned on 2009-09-03
computational Tian W, et al.  (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 YeastFunc
SSL2/YIL143C IDA: Inferred from Direct Assay
Assigned on 2007-10-12
manually curated Guzder SN, et al.  (1994) RAD25 is a DNA helicase required for DNA repair and RNA polymerase II transcription. Nature 369(6481):578-81 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR001161
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
YKU70/YMR284W IEA: Inferred from Electronic Annotation
with EBI:IPR006164, EBI:IPR006165, EBI:IPR005160
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB
YKU80/YMR106C IEA: Inferred from Electronic Annotation
with EBI:IPR005160, EBI:IPR006164
Last Updated 2009-11-20
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. UniProtKB

Graphical Display


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