Ontology: Molecular Function (GO:0003939)

Definition: Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.

Synonyms: glucitol dehydrogenase activity; polyol dehydrogenase activity; sorbitol dehydrogenase activity; L-iditol (sorbitol) dehydrogenase activity; L-iditol:NAD oxidoreductase activity; NAD+-dependent sorbitol dehydrogenase activity; NAD-dependent sorbitol dehydrogenase activity; NAD-sorbitol dehydrogenase; L-iditol:NAD+ 5-oxidoreductase activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term L-iditol 2-dehydrogenase activity (2 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	L-iditol 2-dehydrogenase activity	2
High-throughput	none	none
Computational (download data)	L-iditol 2-dehydrogenase activity	2

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term L-iditol 2-dehydrogenase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

L-iditol 2-dehydrogenase activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
SOR1/YJR159W	IDA: Inferred from Direct Assay, ISS: Inferred from Sequence or structural Similarity with EBI:P07846 Assigned on 2008-07-21	manually curated	Sarthy AV, et al.  (1994) Cloning and sequence determination of the gene encoding sorbitol dehydrogenase from Saccharomyces cerevisiae. Gene 140(1):121-6	SGD
	IEA: Inferred from Electronic Annotation with IUBMB:1.1.1.14 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
SOR2/YDL246C	ISS: Inferred from Sequence or structural Similarity with SGD:SOR1 Assigned on 2008-07-24	manually curated	Gonzalez E, et al.  (2000) Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J Biol Chem 275(46):35876-85	SGD
	IEA: Inferred from Electronic Annotation with IUBMB:1.1.1.14 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB

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