Ontology: Molecular Function (GO:0003825)

Definition: Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.

Synonyms: transglucosylase activity; trehalose 6-phosphate synthase activity; trehalose 6-phosphate synthetase activity; trehalose phosphate synthase activity; trehalose phosphate synthetase activity; trehalose-phosphate synthase activity; trehalose-phosphate synthetase activity; trehalosephosphate-UDP glucosyl transferase activity; trehalosephosphate-UDP glucosyltransferase activity; UDP-glucose-glucose-phosphate glucosyltransferase activity; UDP-glucose-glucosephosphate glucosyltransferase activity; alpha,alpha-trehalose phosphate synthase (UDP-forming); UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity; phosphotrehalose-uridine diphosphate transglucosylase activity; trehalose phosphate-uridine diphosphate glucosyltransferase activity; trehalose-P synthetase activity; UDPglucose-glucose-phosphate glucosyltransferase activity; UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity; uridine diphosphoglucose phosphate glucosyltransferase activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity (1 gene) or to its variants containing one or more qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	1
	contributes_to: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	2
High-throughput	none	none
Computational (download data)	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	1

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

contributes_to: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
TPS3/YMR261C	IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2005-07-29	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD
TSL1/YML100W	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-29	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity      1 gene directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
TPS1/YBR126C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Bell W, et al.  (1992) Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209(3):951-9	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR012766 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with IUBMB:2.4.1.15 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB

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