Ontology: Molecular Function (GO:0003824)

Definition: Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Synonyms: enzyme activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term catalytic activity (398 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	catalytic activity	1
High-throughput	none	none
Computational (download data)	catalytic activity	397

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term catalytic activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

catalytic activity      398 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
AAT1/YKL106W	IEA: Inferred from Electronic Annotation with EBI:IPR004838, EBI:IPR015421, EBI:IPR015422 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
AAT2/YLR027C	IEA: Inferred from Electronic Annotation with EBI:IPR004838, EBI:IPR015421 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ABZ1/YNR033W	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ABZ2/YMR289W	IEA: Inferred from Electronic Annotation with EBI:IPR001544 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ACC1/YNR016C	IEA: Inferred from Electronic Annotation with EBI:IPR005481, EBI:IPR013815 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ACH1/YBL015W	IEA: Inferred from Electronic Annotation with EBI:IPR003702 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ACS1/YAL054C	IEA: Inferred from Electronic Annotation with EBI:IPR000873 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ACS2/YLR153C	IEA: Inferred from Electronic Annotation with EBI:IPR000873 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ADE13/YLR359W	IEA: Inferred from Electronic Annotation with EBI:IPR008948, EBI:IPR020557 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ADE16/YLR028C	IEA: Inferred from Electronic Annotation with EBI:IPR016193 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ADE17/YMR120C	IEA: Inferred from Electronic Annotation with EBI:IPR016193 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ADE2/YOR128C	IEA: Inferred from Electronic Annotation with EBI:IPR013815 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ADE3/YGR204W	IEA: Inferred from Electronic Annotation with EBI:IPR000672, EBI:IPR020630, EBI:IPR020631, EBI:IPR020867 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ADE5,7/YGL234W	IEA: Inferred from Electronic Annotation with EBI:IPR000728, EBI:IPR013815, EBI:IPR016188 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ADE6/YGR061C	IEA: Inferred from Electronic Annotation with EBI:IPR000728, EBI:IPR016188 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
AGX1/YFL030W	IEA: Inferred from Electronic Annotation with EBI:IPR015421, EBI:IPR015422 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
AIM22/YJL046W	IEA: Inferred from Electronic Annotation with EBI:IPR004143 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ALO1/YML086C	IEA: Inferred from Electronic Annotation with EBI:IPR016166, EBI:IPR016167 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ALT1/YLR089C	IEA: Inferred from Electronic Annotation with EBI:IPR015421, EBI:IPR015422 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ALT2/YDR111C	IEA: Inferred from Electronic Annotation with EBI:IPR015421, EBI:IPR015422 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
AMS1/YGL156W	IEA: Inferred from Electronic Annotation with EBI:IPR011330, EBI:IPR011013 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
AOS1/YPR180W	IEA: Inferred from Electronic Annotation with EBI:IPR000594 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
APA1/YCL050C	IEA: Inferred from Electronic Annotation with EBI:IPR011146 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
APA2/YDR530C	IEA: Inferred from Electronic Annotation with EBI:IPR011146 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ARG4/YHR018C	IEA: Inferred from Electronic Annotation with EBI:IPR020557, EBI:IPR008948 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ARG5,6/YER069W	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ARG7/YMR062C	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
ARG8/YOL140W	IEA: Inferred from Electronic Annotation with EBI:IPR015422, EBI:IPR015421 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ARI1/YGL157W	IEA: Inferred from Electronic Annotation with EBI:IPR001509 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
ARO1/YDR127W	IEA: Inferred from Electronic Annotation with EBI:IPR013792, EBI:IPR013785 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
	IEA: Inferred from Electronic Annotation with EBI:KW-0511 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

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