GO term: RNA binding 
Ontology: Molecular Function (GO:0003723)
Definition: Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
View Ontology:
(graph) | 
(text)
Definition: Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
RNA binding (439 genes)
or to its variants containing one or more
qualifiers (15 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | contributes_to: RNA binding | 15 |
| RNA binding | 205 | |
| High-throughput (download data) | RNA binding | 1 |
| Computational (download data) | RNA binding | 378 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
RNA binding or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| contributes_to: RNA binding 15 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| CLP1/YOR250C | IDA: Inferred from Direct Assay Assigned on 2005-02-18 |
manually curated | Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 |
SGD |
| FIP1/YJR093C | IMP: Inferred from Mutant Phenotype Assigned on 2005-02-18 |
manually curated | Helmling S, et al. (2001) Fip1 regulates the activity of Poly(A) polymerase through multiple interactions. Mol Cell Biol 21(6):2026-37 |
SGD |
| LSM2/YBL026W | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-11-29 |
manually curated | Fernandez CF, et al. (2004) An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5. Mol Biol Cell 15(6):2842-52 |
SGD | |
| LSM3/YLR438C-A | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| LSM5/YER146W | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-11-29 |
manually curated | Fernandez CF, et al. (2004) An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5. Mol Biol Cell 15(6):2842-52 |
SGD | |
| LSM6/YDR378C | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-11-29 |
manually curated | Fernandez CF, et al. (2004) An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5. Mol Biol Cell 15(6):2842-52 |
SGD | |
| LSM7/YNL147W | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| LSM8/YJR022W | IPI: Inferred from Physical Interaction Assigned on 2005-11-29 |
manually curated | Salgado-Garrido J, et al. (1999) Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J 18(12):3451-62 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-11-29 |
manually curated | Fernandez CF, et al. (2004) An Lsm2-Lsm7 complex in Saccharomyces cerevisiae associates with the small nucleolar RNA snR5. Mol Biol Cell 15(6):2842-52 |
SGD | |
| MPE1/YKL059C | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-22 |
manually curated | Vo LT, et al. (2001) Mpe1, a zinc knuckle protein, is an essential component of yeast cleavage and polyadenylation factor required for the cleavage and polyadenylation of mRNA. Mol Cell Biol 21(24):8346-56 |
SGD |
| PFS2/YNL317W | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-18 |
manually curated | Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 |
SGD |
| PTA1/YAL043C | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-18 |
manually curated | Zhao J, et al. (1999) Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol Cell Biol 19(11):7733-40 |
SGD |
| PTI1/YGR156W | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-18 |
manually curated | Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 |
SGD |
| RNA14/YMR061W | IDA: Inferred from Direct Assay Assigned on 2005-02-18 |
manually curated | Noble CG, et al. (2004) Rna14-Rna15 assembly mediates the RNA-binding capability of Saccharomyces cerevisiae cleavage factor IA. Nucleic Acids Res 32(11):3364-75 |
SGD |
| SYC1/YOR179C | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-22 |
manually curated | Nedea E, et al. (2003) Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem 278(35):33000-10 |
SGD |
| YSH1/YLR277C | IC: Inferred By Curator from mRNA cleavage and polyadenylation specificity factor complex Assigned on 2005-02-18 |
manually curated | Zhao J, et al. (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8 |
SGD |
| RNA binding 439 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ABD1/YBR236C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AEP2/YMR282C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AI1/Q0050 | IEA: Inferred from Electronic Annotation with EBI:IPR000477 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| AI2/Q0055 | TAS: Traceable Author Statement Assigned on 2002-10-24 |
manually curated | Zimmerly S, et al. (1999) Group II intron reverse transcriptase in yeast mitochondria. Stabilization and regulation of reverse transcriptase activity by the intron RNA. J Mol Biol 289(3):473-90 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR000477 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| AIR2/YDL175C | IDA: Inferred from Direct Assay Assigned on 2012-04-02 |
manually curated | Holub P, et al. (2012) Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation. Nucleic Acids Res 40(12):5679-93 |
SGD |
| ALA1/YOR335C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ANB1/YJR047C | ISA: Inferred from Sequence Alignment with SGD:HYP2 Assigned on 2009-05-15 |
manually curated | Gentz PM, et al. (2009) Dimerization of the yeast eukaryotic translation initiation factor 5A requires hypusine and is RNA dependent. FEBS J 276(3):695-706 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR019769, EBI:IPR020189, EBI:IPR001884 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ARC1/YGL105W | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BFR1/YOR198C | IDA: Inferred from Direct Assay Assigned on 2002-12-04 |
manually curated | Lang BD, et al. (2001) The brefeldin A resistance protein Bfr1p is a component of polyribosome-associated mRNP complexes in yeast. Nucleic Acids Res 29(12):2567-74 |
SGD |
| BI3/Q0115 | IDA: Inferred from Direct Assay Assigned on 2002-11-19 |
manually curated | Bassi GS, et al. (2002) Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A 99(1):128-33 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| BI4/Q0120 | IDA: Inferred from Direct Assay Assigned on 2002-11-19 |
manually curated | Rho SB and Martinis SA (2000) The bI4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity. RNA 6(12):1882-94 |
SGD |
| BRE5/YNR051C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BRR1/YPR057W | IPI: Inferred from Physical Interaction Assigned on 2002-11-01 |
manually curated | Noble SM and Guthrie C (1996) Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs. EMBO J 15(16):4368-79 |
SGD |
| CBC2/YPL178W | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CBF5/YLR175W | IEA: Inferred from Electronic Annotation with EBI:IPR004521, EBI:IPR020103, EBI:IPR002478 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CBP2/YHL038C | IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2009-11-10 |
manually curated | Tirupati HK, et al. (1999) An RNA binding motif in the Cbp2 protein required for protein-stimulated RNA catalysis. J Biol Chem 274(43):30393-401 |
SGD |
| CCA1/YER168C | IEA: Inferred from Electronic Annotation with EBI:IPR002646 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CCR4/YAL021C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CDC33/YOL139C | IEA: Inferred from Electronic Annotation with EBI:IPR001040, EBI:IPR019770 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CFT1/YDR301W | IDA: Inferred from Direct Assay Assigned on 2005-02-16 |
manually curated | Zhao J, et al. (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CFT2/YLR115W | IPI: Inferred from Physical Interaction Assigned on 2005-02-16 |
manually curated | Zhao J, et al. (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8 |
SGD |
| CIC1/YHR052W | IEA: Inferred from Electronic Annotation with EBI:IPR023674, EBI:IPR002143 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| CSL4/YNL232W | IEA: Inferred from Electronic Annotation with EBI:IPR019495 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CTH1/YDR151C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CUS1/YMR240C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CUS2/YNL286W | IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2002-09-26 |
manually curated | Yan D, et al. (1998) CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif. Mol Cell Biol 18(9):5000-9 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CWC2/YDL209C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CWC22/YGR278W | IEA: Inferred from Electronic Annotation with EBI:IPR003890 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| DBP1/YPL119C | IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DBP10/YDL031W | IEA: Inferred from Electronic Annotation with EBI:IPR012541 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0694 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
