Ontology: Cellular Component (GO:0034388)

Definition: A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.

Synonyms: 25-30 S subcomplex of 90S preribosome; UTP-B complex

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term Pwp2p-containing subcomplex of 90S preribosome (6 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	Pwp2p-containing subcomplex of 90S preribosome	6
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

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• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term Pwp2p-containing subcomplex of 90S preribosome or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

Pwp2p-containing subcomplex of 90S preribosome      6 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
DIP2/YLR129W	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD
PWP2/YCR057C	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD
UTP13/YLR222C	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD
UTP18/YJL069C	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD
UTP21/YLR409C	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD
UTP6/YDR449C	IDA: Inferred from Direct Assay Assigned on 2008-04-09	manually curated	Dosil M and Bustelo XR  (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97	SGD
	IDA: Inferred from Direct Assay Assigned on 2008-06-05	manually curated	Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29	SGD

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