Ontology: Cellular Component (GO:0032432)

Definition: An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.

Synonyms: actin cable

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term actin filament bundle (7 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	actin filament bundle	7
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term actin filament bundle or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

actin filament bundle      7 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ABP140/YOR239W	IDA: Inferred from Direct Assay Assigned on 2011-01-13	manually curated	Yang HC and Pon LA  (2002) Actin cable dynamics in budding yeast. Proc Natl Acad Sci U S A 99(2):751-6	SGD
ACT1/YFL039C	IDA: Inferred from Direct Assay Assigned on 2009-11-11	manually curated	Novick P and Botstein D  (1985) Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell 40(2):405-16	SGD
	IDA: Inferred from Direct Assay Assigned on 2009-11-11	manually curated	Kilmartin JV and Adams AE  (1984) Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol 98(3):922-33	SGD
	IDA: Inferred from Direct Assay Assigned on 2009-11-11	manually curated	Mulholland J, et al.  (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91	SGD
MYO2/YOR326W	IMP: Inferred from Mutant Phenotype Assigned on 2006-10-25	manually curated	Pruyne DW, et al.  (1998) Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast. J Cell Biol 143(7):1931-45	SGD
SAC6/YDR129C	IDA: Inferred from Direct Assay Assigned on 2009-11-10	manually curated	Drubin DG, et al.  (1988) Yeast actin-binding proteins: evidence for a role in morphogenesis. J Cell Biol 107(6 Pt 2):2551-61	SGD
SWF1/YDR126W	IDA: Inferred from Direct Assay Assigned on 2009-04-06	manually curated	Dighe SA and Kozminski KG  (2008) Swf1p, a member of the DHHC-CRD family of palmitoyltransferases, regulates the actin cytoskeleton and polarized secretion independently of its DHHC motif. Mol Biol Cell 19(10):4454-68	SGD
TPM1/YNL079C	IDA: Inferred from Direct Assay Assigned on 2003-09-02	manually curated	Pruyne DW, et al.  (1998) Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast. J Cell Biol 143(7):1931-45	SGD
TPM2/YIL138C	IDA: Inferred from Direct Assay Assigned on 2003-09-02	manually curated	Pruyne DW, et al.  (1998) Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast. J Cell Biol 143(7):1931-45	SGD

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