GO term: protein tag 
Ontology: Molecular Function (GO:0031386)
Definition: Acting as an indicator or marker to facilitate recognition by other molecules in the cell. Recognition of the tag, which can be covalently attached to the target molecule, may result in modification, sequestration, transport or degradation of the molecule in question.
Synonyms: protein tagging activity; ubiquitin; covalent modifier
View Ontology:
(graph) | 
(text)
Definition: Acting as an indicator or marker to facilitate recognition by other molecules in the cell. Recognition of the tag, which can be covalently attached to the target molecule, may result in modification, sequestration, transport or degradation of the molecule in question.
Synonyms: protein tagging activity; ubiquitin; covalent modifier
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
protein tag (10 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | protein tag | 10 |
| High-throughput | none | none |
| Computational | none | none |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
protein tag or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| protein tag 10 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ATG12/YBR217W | IPI: Inferred from Physical Interaction with SGD:ATG10 Assigned on 2005-10-17 |
manually curated | Shintani T, et al. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 18(19):5234-41 |
SGD |
| IPI: Inferred from Physical Interaction with SGD:ATG5 Assigned on 2005-10-17 |
manually curated | Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 |
SGD | |
| IPI: Inferred from Physical Interaction with SGD:ATG7 Assigned on 2005-10-17 |
manually curated | Tanida I, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79 |
SGD | |
| ATG8/YBL078C | IMP: Inferred from Mutant Phenotype Assigned on 2013-01-09 |
manually curated | Yu ZQ, et al. (2012) Dual roles of Atg8-PE deconjugation by Atg4 in autophagy. Autophagy 8(6):883-92 |
SGD |
| HUB1/YNR032C-A | IDA: Inferred from Direct Assay, ISS: Inferred from Sequence or structural Similarity Assigned on 2005-05-25 |
manually curated | Dittmar GA, et al. (2002) Role of a ubiquitin-like modification in polarized morphogenesis. Science 295(5564):2442-6 |
SGD |
| RPL40A/YIL148W | ISS: Inferred from Sequence or structural Similarity Assigned on 2005-05-25 |
manually curated | Ozkaynak E, et al. (1987) The yeast ubiquitin genes: a family of natural gene fusions. EMBO J 6(5):1429-39 |
SGD |
| RPL40B/YKR094C | ISS: Inferred from Sequence or structural Similarity Assigned on 2005-05-25 |
manually curated | Ozkaynak E, et al. (1987) The yeast ubiquitin genes: a family of natural gene fusions. EMBO J 6(5):1429-39 |
SGD |
| RPS31/YLR167W | IMP: Inferred from Mutant Phenotype Assigned on 2008-12-05 |
manually curated | Finley D, et al. (1989) The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis. Nature 338(6214):394-401 |
SGD |
| RUB1/YDR139C | IDA: Inferred from Direct Assay, ISS: Inferred from Sequence or structural Similarity with SGD:SMT3, SGD:UBI4 Assigned on 2005-10-18 |
manually curated | Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-04-27 |
manually curated | Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 |
SGD | |
| SMT3/YDR510W | IDA: Inferred from Direct Assay Assigned on 2005-05-25 |
manually curated | Takahashi Y, et al. (1999) Smt3, a SUMO-1 homolog, is conjugated to Cdc3, a component of septin rings at the mother-bud neck in budding yeast. Biochem Biophys Res Commun 259(3):582-7 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-05-25 |
manually curated | Johnson ES and Blobel G (1999) Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins. J Cell Biol 147(5):981-94 |
SGD | |
| ISS: Inferred from Sequence or structural Similarity Assigned on 2005-05-25 |
manually curated | Mahajan R, et al. (1997) A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell 88(1):97-107 |
SGD | |
| UBI4/YLL039C | ISS: Inferred from Sequence or structural Similarity Assigned on 2005-05-25 |
manually curated | Ozkaynak E, et al. (1987) The yeast ubiquitin genes: a family of natural gene fusions. EMBO J 6(5):1429-39 |
SGD |
| URM1/YIL008W | IDA: Inferred from Direct Assay Assigned on 2005-10-21 |
manually curated | Furukawa K, et al. (2000) A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes. J Biol Chem 275(11):7462-5 |
SGD |
| IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2005-05-25 |
manually curated | Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 |
SGD | |
