Ontology: Biological Process (GO:0031120)

Definition: The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term snRNA pseudouridine synthesis (8 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	snRNA pseudouridine synthesis	7
High-throughput	none	none
Computational (download data)	snRNA pseudouridine synthesis	2

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term snRNA pseudouridine synthesis or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

snRNA pseudouridine synthesis      8 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
CBF5/YLR175W	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-06-25	manually curated	Ma X, et al.  (2005) Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. EMBO J 24(13):2403-13	SGD
GAR1/YHR089C	IDA: Inferred from Direct Assay Assigned on 2007-06-25	manually curated	Ma X, et al.  (2005) Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. EMBO J 24(13):2403-13	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR007504 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
NAF1/YNL124W	IEA: Inferred from Electronic Annotation with EBI:IPR007504 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
NHP2/YDL208W	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-06-25	manually curated	Ma X, et al.  (2005) Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. EMBO J 24(13):2403-13	SGD
NOP10/YHR072W-A	IDA: Inferred from Direct Assay Assigned on 2007-06-25	manually curated	Ma X, et al.  (2005) Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. EMBO J 24(13):2403-13	SGD
PUS1/YPL212C	IMP: Inferred from Mutant Phenotype Assigned on 2007-06-25	manually curated	Massenet S, et al.  (1999) Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA. Mol Cell Biol 19(3):2142-54	SGD
PUS7/YOR243C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-06-25	manually curated	Ma X, et al.  (2003) Pseudouridylation (Psi) of U2 snRNA in S. cerevisiae is catalyzed by an RNA-independent mechanism. EMBO J 22(8):1889-97	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2008-06-16	manually curated	Behm-Ansmant I, et al.  (2003) The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. RNA 9(11):1371-82	SGD
SNR81/snR81	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-06-25	manually curated	Ma X, et al.  (2005) Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism. EMBO J 24(13):2403-13	SGD

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