Ontology: Cellular Component (GO:0030686)

Definition: A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term 90S preribosome (79 genes) or to its variants containing one or more qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	90S preribosome	14
	colocalizes_with: 90S preribosome	1
High-throughput (download data)	90S preribosome	69
Computational (download data)	90S preribosome	2

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term 90S preribosome or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

colocalizes_with: 90S preribosome      1 gene directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ESF2/YNR054C	IDA: Inferred from Direct Assay Assigned on 2008-05-16	manually curated	Hoang T, et al.  (2005) Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol 25(13):5523-34	SGD

90S preribosome      79 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
BFR2/YDR299W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
BMS1/YPL217C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
BUD21/YOR078W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
BUD22/YMR014W	IDA: Inferred from Direct Assay Assigned on 2010-05-04	manually curated	Li Z, et al.  (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213	SGD
CBF5/YLR175W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
CMS1/YLR003C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
DBP8/YHR169W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
DIM1/YPL266W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
DIP2/YLR129W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
ECM16/YMR128W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
EMG1/YLR186W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
ENP1/YBR247C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
ENP2/YGR145W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
HAS1/YMR290C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
IMP3/YHR148W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
IMP4/YNL075W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
KRE33/YNL132W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
KRR1/YCL059C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
MPP10/YJR002W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
MRD1/YPR112C	IDA: Inferred from Direct Assay Assigned on 2013-02-04	manually curated	Segerstolpe A, et al.  (2013) Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome. Nucleic Acids Res 41(2):1178-90	SGD
	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NAN1/YPL126W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOC4/YPR144C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOP1/YDL014W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOP14/YDL148C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOP19/YGR251W	IDA: Inferred from Direct Assay Assigned on 2011-09-29	manually curated	Choque E, et al.  (2011) The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit in Saccharomyces cerevisiae. RNA Biol 8(6):1158-72	SGD
NOP56/YLR197W	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOP58/YOR310C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD
NOP6/YDL213C	IDA: Inferred from Direct Assay Assigned on 2011-02-20	manually curated	Garcia-Gomez JJ, et al.  (2011) Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae. RNA Biol 8(1):112-24	SGD
NOP9/YJL010C	IDA: Inferred from Direct Assay Assigned on 2007-12-05	manually curated	Thomson E, et al.  (2007) Nop9 is an RNA binding protein present in pre-40S ribosomes and required for 18S rRNA synthesis in yeast. RNA 13(12):2165-2174	SGD
PNO1/YOR145C	IDA: Inferred from Direct Assay Assigned on 2012-02-08	high-throughput	Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15	SGD

SGD Home About Blog Site Map Help Terms of Use
© Stanford University, Stanford, CA 94305.