Ontology: Molecular Function (GO:0030562)

Definition: Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term rRNA 2'-O-ribose methylation guide activity (43 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	rRNA 2'-O-ribose methylation guide activity	43
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term rRNA 2'-O-ribose methylation guide activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

rRNA 2'-O-ribose methylation guide activity      43 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
SNR128/snR128	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-04-07	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR13/snR13	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR18/snR18	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-04-07	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR190/snR190	ISS: Inferred from Sequence or structural Similarity Assigned on 2002-03-06	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR24/snR24	IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2006-08-23	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR38/snR38	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-08-23	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR39/snR39	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-04-07	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR39B/snR39B	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR40/snR40	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-08-23	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR41/snR41	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
	ISS: Inferred from Sequence or structural Similarity Assigned on 2006-08-23	manually curated	Kiss-Laszlo Z, et al.  (1996) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. Cell 85(7):1077-88	SGD
SNR47/snR47	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR48/snR48	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR50/snR50	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR51/snR51	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR52/snR52	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
	IGI: Inferred from Genetic Interaction with SGD:SPB1, IMP: Inferred from Mutant Phenotype Assigned on 2004-11-19	manually curated	Lapeyre B and Purushothaman SK  (2004) Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage. Mol Cell 16(4):663-9	SGD
SNR53/snR53	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR54/snR54	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR55/snR55	ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR56/snR56	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR57/snR57	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR58/snR58	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR59/snR59	ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR60/snR60	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR61/snR61	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR62/snR62	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR63/snR63	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR64/snR64	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR65/snR65	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR66/snR66	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD
SNR67/snR67	IMP: Inferred from Mutant Phenotype, ISM: Inferred from Sequence Model Assigned on 2008-04-16	manually curated	Lowe TM and Eddy SR  (1999) A computational screen for methylation guide snoRNAs in yeast. Science 283(5405):1168-71	SGD

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