Ontology: Biological Process (GO:0030543)

Definition: The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.

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This table lists the methods used to annotate genes either directly to the term 2-micrometer plasmid partitioning (4 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	2-micrometer plasmid partitioning	4
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term 2-micrometer plasmid partitioning or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

2-micrometer plasmid partitioning      4 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
CSE4/YKL049C	IMP: Inferred from Mutant Phenotype Assigned on 2006-10-26	manually curated	Hajra S, et al.  (2006) The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation. J Cell Biol 174(6):779-90	SGD
REP1/R0020C	IMP: Inferred from Mutant Phenotype Assigned on 2006-10-26	manually curated	Ahn YT, et al.  (1997) The 2microm-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus. J Bacteriol 179(23):7497-506	SGD
REP2/R0040C	IMP: Inferred from Mutant Phenotype Assigned on 2006-10-26	manually curated	Ahn YT, et al.  (1997) The 2microm-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus. J Bacteriol 179(23):7497-506	SGD
SCC2/YDR180W	IC: Inferred By Curator from 2-micrometer circle DNA Assigned on 2010-02-24	manually curated	Ghosh SK, et al.  (2007) Faithful segregation of the multicopy yeast plasmid through cohesin-mediated recognition of sisters. Proc Natl Acad Sci U S A 104(32):13034-9	SGD

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