GO term: actin cortical patch 
Ontology: Cellular Component (GO:0030479)
Definition: A discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
Synonyms: actin patch
View Ontology:
(graph) | 
(text)
Definition: A discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
Synonyms: actin patch
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
actin cortical patch (59 genes)
or to its variants containing one or more
qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | actin cortical patch | 50 |
| colocalizes_with: actin cortical patch | 1 | |
| NOT: actin cortical patch | 1 | |
| High-throughput | none | none |
| Computational (download data) | actin cortical patch | 30 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
actin cortical patch or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| colocalizes_with: actin cortical patch 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| LDB17/YDL146W | IDA: Inferred from Direct Assay Assigned on 2009-06-24 |
manually curated | Burston HE, et al. (2009) Regulators of yeast endocytosis identified by systematic quantitative analysis. J Cell Biol 185(6):1097-110 |
SGD |
| NOT: actin cortical patch 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| SUR7/YML052W | IDA: Inferred from Direct Assay Assigned on 2002-06-12 |
manually curated | Young ME, et al. (2002) The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Mol Cell Biol 22(3):927-34 |
SGD |
| actin cortical patch 59 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ABP1/YCR088W | IDA: Inferred from Direct Assay Assigned on 2009-11-10 |
manually curated | Drubin DG, et al. (1988) Yeast actin-binding proteins: evidence for a role in morphogenesis. J Cell Biol 107(6 Pt 2):2551-61 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ABP140/YOR239W | IDA: Inferred from Direct Assay Assigned on 2011-01-13 |
manually curated | Asakura T, et al. (1998) Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene 16(1):121-30 |
SGD |
| ACT1/YFL039C | IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Novick P and Botstein D (1985) Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell 40(2):405-16 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Kilmartin JV and Adams AE (1984) Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol 98(3):922-33 |
SGD | |
| IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 |
SGD | |
| AIM21/YIR003W | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AIM3/YBR108W | IDA: Inferred from Direct Assay Assigned on 2011-01-04 |
manually curated | Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 |
SGD |
| AIM7/YDR063W | IDA: Inferred from Direct Assay Assigned on 2010-07-20 |
manually curated | Gandhi M, et al. (2010) GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 20(9):861-7 |
SGD |
| AIP1/YMR092C | IDA: Inferred from Direct Assay Assigned on 2013-02-17 |
manually curated | Rodal AA, et al. (1999) Aip1p interacts with cofilin to disassemble actin filaments. J Cell Biol 145(6):1251-64 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| APP1/YNL094W | IDA: Inferred from Direct Assay Assigned on 2003-05-12 |
manually curated | Drees BL, et al. (2001) A protein interaction map for cell polarity development. J Cell Biol 154(3):549-71 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ARC15/YIL062C | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARC19/YKL013C | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARC35/YNR035C | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARC40/YBR234C | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARK1/YNL020C | IDA: Inferred from Direct Assay Assigned on 2008-10-13 |
manually curated | Cope MJ, et al. (1999) Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast. J Cell Biol 144(6):1203-18 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ARP2/YDL029W | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARP3/YJR065C | IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BBC1/YJL020C | IDA: Inferred from Direct Assay Assigned on 2005-11-07 |
manually curated | Tong AH, et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2002-11-26 |
manually curated | Mochida J, et al. (2002) The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae. Genetics 160(3):923-34 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| BSP1/YPR171W | IDA: Inferred from Direct Assay Assigned on 2003-04-29 |
manually curated | Wicky S, et al. (2003) Bsp1p/Ypr171p is an adapter that directly links some synaptojanin family members to the cortical actin cytoskeleton in yeast. FEBS Lett 537(1-3):35-41 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| BZZ1/YHR114W | IDA: Inferred from Direct Assay Assigned on 2002-12-18 |
manually curated | Soulard A, et al. (2002) Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol 22(22):7889-906 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CAP1/YKL007W | IDA: Inferred from Direct Assay Assigned on 2004-09-30 |
manually curated | Kim K, et al. (2004) Capping protein binding to actin in yeast: biochemical mechanism and physiological relevance. J Cell Biol 164(4):567-80 |
SGD |
| CAP2/YIL034C | IDA: Inferred from Direct Assay Assigned on 2004-09-30 |
manually curated | Kim K, et al. (2004) Capping protein binding to actin in yeast: biochemical mechanism and physiological relevance. J Cell Biol 164(4):567-80 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| COF1/YLL050C | IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2009-11-11 |
manually curated | Moon AL, et al. (1993) Cofilin is an essential component of the yeast cortical cytoskeleton. J Cell Biol 120(2):421-35 |
SGD | |
| CRN1/YLR429W | IDA: Inferred from Direct Assay Assigned on 2008-02-26 |
manually curated | Heil-Chapdelaine RA, et al. (1998) The role of Saccharomyces cerevisiae coronin in the actin and microtubule cytoskeletons. Curr Biol 8(23):1281-4 |
SGD |
| EDE1/YBL047C | IDA: Inferred from Direct Assay Assigned on 2001-02-06 |
manually curated | Gagny B, et al. (2000) A novel EH domain protein of Saccharomyces cerevisiae, Ede1p, involved in endocytosis. J Cell Sci 113 ( Pt 18)():3309-19 |
SGD |
| END3/YNL084C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:SL-0008 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ENT1/YDL161W | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| ENT2/YLR206W | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| ENT3/YJR125C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| ENT4/YLL038C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| FKS1/YLR342W | IDA: Inferred from Direct Assay Assigned on 2005-02-16 |
manually curated | Utsugi T, et al. (2002) Movement of yeast 1,3-beta-glucan synthase is essential for uniform cell wall synthesis. Genes Cells 7(1):1-9 |
SGD |
| GTS1/YGL181W | IDA: Inferred from Direct Assay Assigned on 2007-09-13 |
manually curated | Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85 |
SGD |
