GO term: COPII vesicle coat 
Ontology: Cellular Component (GO:0030127)
Definition: One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
Definition: One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
This table lists the methods used to annotate genes either directly to the term
COPII vesicle coat (8 genes)
or to its variants containing one or more
qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | colocalizes_with: COPII vesicle coat | 1 |
| COPII vesicle coat | 7 | |
| High-throughput | none | none |
| Computational (download data) | COPII vesicle coat | 5 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
COPII vesicle coat or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| colocalizes_with: COPII vesicle coat 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| GRH1/YDR517W | IDA: Inferred from Direct Assay Assigned on 2007-06-05 |
manually curated | Behnia R, et al. (2007) The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. J Cell Biol 176(3):255-61 |
SGD |
| COPII vesicle coat 8 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| SAR1/YPL218W | IDA: Inferred from Direct Assay Assigned on 2007-03-29 |
manually curated | Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 |
SGD |
| SEC13/YLR208W | IDA: Inferred from Direct Assay Assigned on 2009-12-15 |
manually curated | Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-09-26 |
manually curated | Pryer NK, et al. (1993) Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J Cell Biol 120(4):865-75 |
SGD | |
| SEC23/YPR181C | IDA: Inferred from Direct Assay Assigned on 2010-01-05 |
manually curated | Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR006895, EBI:IPR006896, EBI:IPR006900 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| SEC24/YIL109C | IDA: Inferred from Direct Assay Assigned on 2009-12-15 |
manually curated | Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR006895, EBI:IPR006896, EBI:IPR006900 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| SEC31/YDL195W | IDA: Inferred from Direct Assay Assigned on 2009-12-16 |
manually curated | Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 |
SGD |
| SFB2/YNL049C | IPI: Inferred from Physical Interaction with SGD:SEC23 Assigned on 2010-01-05 |
manually curated | Peng R, et al. (2000) Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members. J Biol Chem 275(15):11521-8 |
SGD |
| IPI: Inferred from Physical Interaction with SGD:SEC23 Assigned on 2010-01-05 |
manually curated | Higashio H, et al. (2000) Sfb2p, a yeast protein related to Sec24p, can function as a constituent of COPII coats required for vesicle budding from the endoplasmic reticulum. J Biol Chem 275(23):17900-8 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:IPR006895, EBI:IPR006896, EBI:IPR006900 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| SFB3/YHR098C | IDA: Inferred from Direct Assay Assigned on 2010-01-05 |
manually curated | Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2010-01-05 |
manually curated | Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:IPR006895, EBI:IPR006896, EBI:IPR006900 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| YHR035W | IEA: Inferred from Electronic Annotation with EBI:IPR006895, EBI:IPR006896 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
View term lineage as a textual display using
View term lineage as a textual display using