GO term: establishment of cell polarity 
Ontology: Biological Process (GO:0030010)
Definition: The specification and formation of anisotropic intracellular organization or cell growth patterns.
Synonyms: cell polarization; bud site selection/establishment of cell polarity
Definition: The specification and formation of anisotropic intracellular organization or cell growth patterns.
Synonyms: cell polarization; bud site selection/establishment of cell polarity
This table lists the methods used to annotate genes either directly to the term
establishment of cell polarity (49 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | establishment of cell polarity | 48 |
| High-throughput | none | none |
| Computational (download data) | establishment of cell polarity | 1 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
establishment of cell polarity or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| establishment of cell polarity 49 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ABP1/YCR088W | IMP: Inferred from Mutant Phenotype Assigned on 2001-03-02 |
manually curated | Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 |
SGD |
| ACT1/YFL039C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Botstein D, et al. (1997) "The yeast cytoskeleton." Pp. 1-90 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Cell Cycle and Cell Biology, edited by Pringle JR, Broach JR and Jones EW. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press |
SGD |
| BCK1/YJL095W | IMP: Inferred from Mutant Phenotype Assigned on 2001-03-02 |
manually curated | Costigan C, et al. (1992) A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth. Mol Cell Biol 12(3):1162-78 |
SGD |
| BEM1/YBR200W | TAS: Traceable Author Statement Assigned on 2002-08-07 |
manually curated | Bose I, et al. (2001) Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p. J Biol Chem 276(10):7176-86 |
SGD |
| BEM2/YER155C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744 |
SGD |
| BEM3/YPL115C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744 |
SGD |
| BEM4/YPL161C | IMP: Inferred from Mutant Phenotype Assigned on 2001-03-02 |
manually curated | Mack D, et al. (1996) Identification of the bud emergence gene BEM4 and its interactions with rho-type GTPases in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4387-95 |
SGD |
| BNI1/YNL271C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci 113 ( Pt 3):365-75 |
SGD |
| BOI1/YBL085W | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci 113 ( Pt 3):365-75 |
SGD |
| BOI2/YER114C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci 113 ( Pt 3):365-75 |
SGD |
| BUD6/YLR319C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci 113 ( Pt 3):365-75 |
SGD |
| CDC10/YCR002C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Longtine MS, et al. (1996) The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 8(1):106-19 |
SGD |
| CDC11/YJR076C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Longtine MS, et al. (1996) The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 8(1):106-19 |
SGD |
| CDC12/YHR107C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Longtine MS, et al. (1996) The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 8(1):106-19 |
SGD |
| CDC24/YAL041W | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744 |
SGD |
| CDC3/YLR314C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Longtine MS, et al. (1996) The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 8(1):106-19 |
SGD |
| CDC42/YLR229C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744 |
SGD |
| CDC43/YGL155W | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744 |
SGD |
| CKA1/YIL035C | IMP: Inferred from Mutant Phenotype Assigned on 2001-03-02 |
manually curated | Glover CV 3rd (1998) On the physiological role of casein kinase II in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 59():95-133 |
SGD |
| CKA2/YOR061W | IPI: Inferred from Physical Interaction Assigned on 2001-03-02 |
manually curated | Glover CV 3rd (1998) On the physiological role of casein kinase II in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 59():95-133 |
SGD |
| CKB1/YGL019W | IPI: Inferred from Physical Interaction Assigned on 2001-03-02 |
manually curated | Glover CV 3rd (1998) On the physiological role of casein kinase II in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 59():95-133 |
SGD |
| CKB2/YOR039W | IPI: Inferred from Physical Interaction Assigned on 2001-03-02 |
manually curated | Glover CV 3rd (1998) On the physiological role of casein kinase II in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 59():95-133 |
SGD |
| CLA4/YNL298W | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| EXO84/YBR102C | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| GIC1/YHR061C | IGI: Inferred from Genetic Interaction with SGD:GIC2 Assigned on 2008-09-12 |
manually curated | Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 |
SGD |
| GIC2/YDR309C | IGI: Inferred from Genetic Interaction with SGD:GIC1 Assigned on 2008-09-12 |
manually curated | Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 |
SGD |
| LAS1/YKR063C | IMP: Inferred from Mutant Phenotype Assigned on 2001-03-02 |
manually curated | Doseff AI and Arndt KT (1995) LAS1 is an essential nuclear protein involved in cell morphogenesis and cell surface growth. Genetics 141(3):857-71 |
SGD |
| MSB1/YOR188W | IGI: Inferred from Genetic Interaction Assigned on 2002-11-01 |
manually curated | Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 |
SGD |
| MSB2/YGR014W | IGI: Inferred from Genetic Interaction Assigned on 2001-03-02 |
manually curated | Bender A and Pringle JR (1992) A Ser/Thr-rich multicopy suppressor of a cdc24 bud emergence defect. Yeast 8(4):315-23 |
SGD |
| PEA2/YER149C | TAS: Traceable Author Statement Assigned on 2001-03-02 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci 113 ( Pt 3):365-75 |
SGD |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
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