Ontology: Molecular Function (GO:0000030)

Definition: Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mannosyltransferase activity (22 genes) or to its variants containing one or more qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	contributes_to: mannosyltransferase activity	2
	mannosyltransferase activity	13
High-throughput	none	none
Computational (download data)	mannosyltransferase activity	15

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mannosyltransferase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mannosyltransferase activity      22 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ALG9/YNL219C	IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2002-11-15	manually curated	Burda P, et al.  (1996) Stepwise assembly of the lipid-linked oligosaccharide in the endoplasmic reticulum of Saccharomyces cerevisiae: identification of the ALG9 gene encoding a putative mannosyl transferase. Proc Natl Acad Sci U S A 93(14):7160-5	SGD
ANP1/YEL036C	ISS: Inferred from Sequence or structural Similarity Assigned on 2002-02-13	manually curated	Hashimoto H and Yoda K  (1997) Novel membrane protein complexes for protein glycosylation in the yeast Golgi apparatus. Biochem Biophys Res Commun 241(3):682-6	SGD
CSH1/YBR161W	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2004-01-02	manually curated	Uemura S, et al.  (2003) Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p. J Biol Chem 278(46):45049-55	SGD
GPI14/YJR013W	ISS: Inferred from Sequence or structural Similarity Assigned on 2003-02-10	manually curated	Maeda Y, et al.  (2001) PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER. EMBO J 20(1-2):250-61	SGD
GPI18/YBR004C	IGI: Inferred from Genetic Interaction with GenBank/EMBL/DDBJ:BAA91196, ISS: Inferred from Sequence or structural Similarity with GenBank/EMBL/DDBJ:BAA91196 Assigned on 2005-01-03	manually curated	Kang JY, et al.  (2005) PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol. J Biol Chem 280(10):9489-97	SGD
	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2005-03-17	manually curated	Fabre AL, et al.  (2005) Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly. FEBS J 272(5):1160-8	SGD
KRE2/YDR483W	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR1/YOR099W	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR2/YKR061W	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1996) Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem 271(18):11001-8	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR3/YBR205W	IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1997) The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains. J Biol Chem 272(24):15527-31	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR4/YBR199W	ISS: Inferred from Sequence or structural Similarity Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1999) The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae. Biochim Biophys Acta 1426(2):323-34	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR5/YNL029C	ISS: Inferred from Sequence or structural Similarity Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1999) The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae. Biochim Biophys Acta 1426(2):323-34	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR6/YPL053C	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
KTR7/YIL085C	ISS: Inferred from Sequence or structural Similarity Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1999) The KTR and MNN1 mannosyltransferase families of Saccharomyces cerevisiae. Biochim Biophys Acta 1426(2):323-34	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PGA1/YNL158W	IMP: Inferred from Mutant Phenotype Assigned on 2010-08-16	manually curated	Sato K, et al.  (2007) Pga1 Is an Essential Component of Glycosylphosphatidylinositol-Mannosyltransferase II of Saccharomyces cerevisiae. Mol Biol Cell 18(9):3472-85	SGD
PMT1/YDL095W	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PMT2/YAL023C	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PMT3/YOR321W	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PMT4/YJR143C	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PMT5/YDL093W	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
PMT6/YGR199W	IEA: Inferred from Electronic Annotation with EBI:IPR003342 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
SUR1/YPL057C	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2004-01-02	manually curated	Uemura S, et al.  (2003) Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p. J Biol Chem 278(46):45049-55	SGD
YUR1/YJL139C	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Lussier M, et al.  (1996) Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem 271(18):11001-8	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002685 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro

contributes_to: mannosyltransferase activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
PBN1/YCL052C	IMP: Inferred from Mutant Phenotype Assigned on 2005-02-10	manually curated	Ashida H, et al.  (2005) Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I. Mol Biol Cell 16(3):1439-48	SGD
PGA1/YNL158W	IGI: Inferred from Genetic Interaction with SGD:GPI18, IPI: Inferred from Physical Interaction with SGD:GPI18 Assigned on 2007-07-13	manually curated	Sato K, et al.  (2007) Pga1 Is an Essential Component of Glycosylphosphatidylinositol-Mannosyltransferase II of Saccharomyces cerevisiae. Mol Biol Cell 18(9):3472-85	SGD

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