GO term: tRNA wobble uridine modification Help



Ontology: Biological Process (GO:0002098)

Definition: The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term tRNA wobble uridine modification (23 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) tRNA wobble uridine modification 22
High-throughput none none
Computational (download data) tRNA wobble uridine modification 1

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term tRNA wobble uridine modification or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

tRNA wobble uridine modification
     23 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ATS1/YAL020C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
CFD1/YIL003W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
CIA1/YDR267C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
ELP2/YGR200C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
ELP3/YPL086C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
ELP4/YPL101W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
ELP6/YMR312W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
HRR25/YPL204W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
IKI3/YLR384C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
ISU1/YPL135W IGI: Inferred from Genetic Interaction
with SGD:ISU2
Assigned on 2009-03-11
manually curated Nakai Y, et al.  (2007) Thio Modification of Yeast Cytosolic tRNA Is an Iron-Sulfur Protein-Dependent Pathway. Mol Cell Biol 27(8):2841-7 SGD
ISU2/YOR226C IGI: Inferred from Genetic Interaction
with SGD:ISU1
Assigned on 2009-03-11
manually curated Nakai Y, et al.  (2007) Thio Modification of Yeast Cytosolic tRNA Is an Iron-Sulfur Protein-Dependent Pathway. Mol Cell Biol 27(8):2841-7 SGD
KTI11/YBL071W-A IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
KTI12/YKL110C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
MTO1/YGL236C IEA: Inferred from Electronic Annotation
with EBI:IPR004416
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
NBP35/YGL091C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
NCS6/YGL211W IMP: Inferred from Mutant Phenotype
Assigned on 2007-07-11
manually curated Bjork GR, et al.  (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 SGD
IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
NFS1/YCL017C IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
SAP185/YJL098W IGI: Inferred from Genetic Interaction
with SGD:SAP190
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
SAP190/YKR028W IGI: Inferred from Genetic Interaction
with SGD:SAP185
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
SIT4/YDL047W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
TRM9/YML014W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
TUM1/YOR251C IMP: Inferred from Mutant Phenotype
Assigned on 2008-09-15
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD
URM1/YIL008W IMP: Inferred from Mutant Phenotype
Assigned on 2009-03-11
manually curated Huang B, et al.  (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD