GO term: hydrolase activity Help



Ontology: Molecular Function (GO:0016787)

Definition: Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term hydrolase activity (652 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) hydrolase activity 4
High-throughput none none
Computational (download data) hydrolase activity 652

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term hydrolase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

hydrolase activity
     652 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ECM16/YMR128W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ECM32/YER176W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ECM38/YLR299W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EEB1/YPL095C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EHD3/YDR036C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EHT1/YBR177C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ENA1/YDR040C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ENA2/YDR039C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ENA5/YDR038C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ESP1/YGR098C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EXG1/YLR300W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EXG2/YDR261C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EXO1/YOR033C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
EXO5/YBR163W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FAL1/YDR021W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FAS1/YKL182W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FBP1/YLR377C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FBP26/YJL155C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FCP1/YMR277W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FCY1/YPR062W IEA: Inferred from Electronic Annotation
with EBI:IPR002125, EBI:IPR016192
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FIG4/YNL325C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMP30/YPL103C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMP41/YNL168C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FOL2/YGR267C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FRA1/YLL029W IEA: Inferred from Electronic Annotation
with EBI:IPR000587
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FSH1/YHR049W ISS: Inferred from Sequence or structural Similarity
with Protein Data Bank:1aur
Assigned on 2009-03-09
manually curated Quevillon-Cheruel S, et al.  (2005) Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein Sci 14(5):1350-6 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FSH2/YMR222C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FSH3/YOR280C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FUN30/YAL019W IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FZO1/YBR179C IEA: Inferred from Electronic Annotation
with EBI:KW-0378
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB