GO term: RSC complex

Ontology: Cellular Component (GO:0016586)

Definition: A protein complex similar to, but more abundant than, the Swi/Snf complex. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.

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Annotation Summary

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This table lists the methods used to annotate genes either directly to the term RSC complex (18 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	RSC complex	18
High-throughput	none	none
Computational (download data)	RSC complex	2

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Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Genes Annotated with this Term

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Annotation details for genes that have been directly annotated to the term RSC complex or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

RSC complex 18 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ARP7/YPR034W	IDA: Inferred from Direct Assay Assigned on 2004-07-27	manually curated	Cairns BR, et al. (1998) Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. Mol Cell 2(5):639-51	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-24	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
ARP9/YMR033W	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Cairns BR, et al. (1998) Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. Mol Cell 2(5):639-51	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
HTL1/YCR020W-B	IDA: Inferred from Direct Assay Assigned on 2003-01-08	manually curated	Romeo MJ, et al. (2002) HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae. Mol Cell Biol 22(23):8165-74	SGD
LDB7/YBL006C	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
	IGI: Inferred from Genetic Interaction with SGD:RSC3, IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction with SGD:RSC3, SGD:STH1 Assigned on 2006-03-28	manually curated	Wilson B, et al. (2006) The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles. Genetics 172(2):795-809	SGD
NPL6/YMR091C	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
	IDA: Inferred from Direct Assay Assigned on 2012-02-13	manually curated	Baetz KK, et al. (2004) The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol 24(3):1232-44	SGD
RSC1/YGR056W	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
RSC1/YGR056W	IEA: Inferred from Electronic Annotation with EBI:IPR027180 Last Updated 2013-03-02	computational	DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
RSC2/YLR357W	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR027180 Last Updated 2013-03-02	computational	DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
RSC3/YDR303C	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
RSC3/YDR303C	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Angus-Hill ML, et al. (2001) A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. Mol Cell 7(4):741-51	UniProtKB
RSC30/YHR056C	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Angus-Hill ML, et al. (2001) A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. Mol Cell 7(4):741-51	UniProtKB
RSC30/YHR056C	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
RSC4/YKR008W	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
RSC4/YKR008W	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
RSC58/YLR033W	IDA: Inferred from Direct Assay Assigned on 2002-09-25	manually curated	Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38	SGD
RSC6/YCR052W	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Cairns BR, et al. (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
RSC8/YFR037C	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Cairns BR, et al. (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
RSC9/YML127W	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2004-10-06	manually curated	Damelin M, et al. (2002) The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Mol Cell 9(3):563-73	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
RTT102/YGR275W	IDA: Inferred from Direct Assay Assigned on 2012-02-13	manually curated	Baetz KK, et al. (2004) The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol 24(3):1232-44	SGD
SFH1/YLR321C	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Cao Y, et al. (1997) Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression. Mol Cell Biol 17(6):3323-34	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
STH1/YIL126W	IDA: Inferred from Direct Assay Assigned on 2007-01-19	manually curated	Cairns BR, et al. (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60	UniProtKB
	IDA: Inferred from Direct Assay Assigned on 2007-01-31	manually curated	Cairns BR, et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4(5):715-23	SGD
	IDA: Inferred from Direct Assay Assigned on 2007-01-23	manually curated	Saha A, et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16(16):2120-34	SGD
TAF14/YPL129W	IPI: Inferred from Physical Interaction with SGD:STH1 Assigned on 2009-08-19	manually curated	Kabani M, et al. (2005) Anc1 interacts with the catalytic subunits of the general transcription factors TFIID and TFIIF, the chromatin remodeling complexes RSC and INO80, and the histone acetyltransferase complex NuA3. Biochem Biophys Res Commun 332(2):398-403	SGD

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