Ontology: Biological Process (GO:0016237)

Definition: The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term microautophagy (10 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	microautophagy	10
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term microautophagy or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

microautophagy      10 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
CMD1/YBR109C	IMP: Inferred from Mutant Phenotype Assigned on 2007-07-13	manually curated	Uttenweiler A, et al.  (2005) Microautophagic vacuole invagination requires calmodulin in a Ca2+-independent function. J Biol Chem 280(39):33289-97	SGD
GTR2/YGR163W	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-18	manually curated	Dubouloz F, et al.  (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26	SGD
MEH1/YKR007W	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-18	manually curated	Dubouloz F, et al.  (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26	SGD
NVJ1/YHR195W	IMP: Inferred from Mutant Phenotype Assigned on 2003-02-13	manually curated	Roberts P, et al.  (2003) Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol Biol Cell 14(1):129-41	SGD
PEP4/YPL154C	IMP: Inferred from Mutant Phenotype Assigned on 2003-02-13	manually curated	Roberts P, et al.  (2003) Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol Biol Cell 14(1):129-41	SGD
SLM4/YBR077C	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-18	manually curated	Dubouloz F, et al.  (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26	SGD
VTC1/YER072W	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-08-22	manually curated	Uttenweiler A, et al.  (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75	SGD
VTC2/YFL004W	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-08-22	manually curated	Uttenweiler A, et al.  (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75	SGD
VTC3/YPL019C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-08-22	manually curated	Uttenweiler A, et al.  (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75	SGD
VTC4/YJL012C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2007-08-22	manually curated	Uttenweiler A, et al.  (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75	SGD

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