Ontology: Biological Process (GO:0001510)

Definition: Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term RNA methylation (6 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	RNA methylation	1
High-throughput	none	none
Computational (download data)	RNA methylation	6

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term RNA methylation or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

RNA methylation      6 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
MRM1/YOR201C	IEA: Inferred from Electronic Annotation with EBI:IPR001537, EBI:IPR004441 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	GOC
MRM2/YGL136C	IEA: Inferred from Electronic Annotation with EBI:IPR015507 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
SPB1/YCL054W	IEA: Inferred from Electronic Annotation with EBI:IPR015507 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TGS1/YPL157W	IMP: Inferred from Mutant Phenotype Assigned on 2011-03-22	manually curated	Mouaikel J, et al.  (2002) Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell 9(4):891-901	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR019012 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TRM2/YKR056W	IEA: Inferred from Electronic Annotation with EBI:IPR010280 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	GOC
TRM7/YBR061C	IEA: Inferred from Electronic Annotation with EBI:IPR015507 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro

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