GO term: establishment of mitotic spindle orientation Help


Ontology: Biological Process (GO:0000132)

Definition: A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.

Synonyms: establishment of spindle orientation during mitosis; mitotic spindle orientation; orienting of mitotic spindle

Annotation Summary


This table lists the methods used to annotate genes either directly to the term establishment of mitotic spindle orientation (11 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) establishment of mitotic spindle orientation 11
High-throughput none none
Computational none none

Links to Additional Annotations:
Genes Annotated with this Term


Annotation details for genes that have been directly annotated to the term establishment of mitotic spindle orientation or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

establishment of mitotic spindle orientation
     11 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ACT1/YFL039C TAS: Traceable Author Statement
Assigned on 2004-01-28
manually curated Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 SGD
ARP1/YHR129C IMP: Inferred from Mutant Phenotype
Assigned on 2005-05-12
manually curated Muhua L, et al.  (1994) A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration. Cell 78(4):669-79 SGD
BNI1/YNL271C IMP: Inferred from Mutant Phenotype
Assigned on 2004-01-28
manually curated Lee L, et al.  (1999) Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p. J Cell Biol 144(5):947-61 SGD
CIK1/YMR198W TAS: Traceable Author Statement
Assigned on 2004-01-28
manually curated Cottingham FR, et al.  (1999) Novel roles for saccharomyces cerevisiae mitotic spindle motors. J Cell Biol 147(2):335-50 SGD
DMA1/YHR115C IGI: Inferred from Genetic Interaction
with SGD:DMA2
Assigned on 2004-09-21
manually curated Fraschini R, et al.  (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 SGD
DMA2/YNL116W IGI: Inferred from Genetic Interaction
with SGD:DMA1
Assigned on 2004-09-21
manually curated Fraschini R, et al.  (2004) Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15(8):3796-810 SGD
DYN1/YKR054C IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype
Assigned on 2004-01-28
manually curated Cottingham FR and Hoyt MA  (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53 SGD
KIP3/YGL216W IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype
Assigned on 2004-01-28
manually curated Cottingham FR and Hoyt MA  (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53 SGD
IMP: Inferred from Mutant Phenotype
Assigned on 2009-02-27
manually curated Gupta ML Jr, et al.  (2006) Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle. Nat Cell Biol 8(9):913-23 SGD
LDB18/YLL049W IMP: Inferred from Mutant Phenotype
Assigned on 2009-05-21
manually curated Amaro IA, et al.  (2008) The Saccharomyces cerevisiae Homolog of p24 Is Essential for Maintaining the Association of p150Glued With the Dynactin Complex. Genetics 178(2):703-9 SGD
MYO2/YOR326W IMP: Inferred from Mutant Phenotype,
IPI: Inferred from Physical Interaction
with SGD:KAR9
Assigned on 2006-10-19
manually curated Yin H, et al.  (2000) Myosin V orientates the mitotic spindle in yeast. Nature 406(6799):1013-5 SGD
NIP100/YPL174C IMP: Inferred from Mutant Phenotype
Assigned on 2005-05-12
manually curated Kahana JA, et al.  (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell 9(7):1741-56 SGD

Graphical Display


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