Ontology: Biological Process (GO:0000001)

Definition: The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.

Synonyms: mitochondrial inheritance

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mitochondrion inheritance (27 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	mitochondrion inheritance	27
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mitochondrion inheritance or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mitochondrion inheritance      27 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ABF2/YMR072W	IMP: Inferred from Mutant Phenotype Assigned on 2002-09-17	manually curated	Zelenaya-Troitskaya O, et al.  (1998) Functions of the high mobility group protein, Abf2p, in mitochondrial DNA segregation, recombination and copy number in Saccharomyces cerevisiae. Genetics 148(4):1763-76	SGD
ACT1/YFL039C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
ADY3/YDL239C	IGI: Inferred from Genetic Interaction with SGD:GIP1, IMP: Inferred from Mutant Phenotype Assigned on 2008-10-13	manually curated	Suda Y, et al.  (2007) Alternative Modes of Organellar Segregation during Sporulation in Saccharomyces cerevisiae. Eukaryot Cell 6(11):2009-17	SGD
ARC15/YIL062C	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
ARC18/YLR370C	TAS: Traceable Author Statement Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
ARC19/YKL013C	TAS: Traceable Author Statement Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
ARC35/YNR035C	TAS: Traceable Author Statement Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
ARP2/YDL029W	IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
ARP3/YJR065C	TAS: Traceable Author Statement Assigned on 2005-02-21	manually curated	Boldogh IR, et al.  (2001) Arp2/3 complex and actin dynamics are required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci U S A 98(6):3162-7	SGD
BUL1/YMR275C	IGI: Inferred from Genetic Interaction Assigned on 2001-01-18	manually curated	Fisk HA and Yaffe MP  (1999) A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae. J Cell Biol 145(6):1199-208	SGD
DNM1/YLL001W	IGI: Inferred from Genetic Interaction with SGD:NUM1 Assigned on 2007-03-19	manually curated	Cerveny KL, et al.  (2007) Yeast mitochondrial division and distribution require the cortical num1 protein. Dev Cell 12(3):363-75	SGD
GEM1/YAL048C	IGI: Inferred from Genetic Interaction with SGD:YPT11, SGD:MMR1, IMP: Inferred from Mutant Phenotype Assigned on 2008-06-05	manually curated	Frederick RL, et al.  (2008) Multiple pathways influence mitochondrial inheritance in budding yeast. Genetics 178(2):825-37	SGD
MDM1/YML104C	IDA: Inferred from Direct Assay Assigned on 2002-08-06	manually curated	Fisk HA and Yaffe MP  (1997) Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance. J Cell Biol 138(3):485-94	SGD
MDM12/YOL009C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Hermann GJ and Shaw JM  (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303	SGD
MDM20/YOL076W	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2002-05-17	manually curated	Hermann GJ, et al.  (1997) The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton. J Cell Biol 137(1):141-53	SGD
MDM31/YHR194W	IMP: Inferred from Mutant Phenotype Assigned on 2005-02-08	manually curated	Dimmer KS, et al.  (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15	SGD
MDM32/YOR147W	IMP: Inferred from Mutant Phenotype Assigned on 2005-02-08	manually curated	Dimmer KS, et al.  (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15	SGD
MMR1/YLR190W	IMP: Inferred from Mutant Phenotype Assigned on 2005-02-08	manually curated	Itoh T, et al.  (2004) Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast. EMBO J 23(13):2520-30	SGD
	IGI: Inferred from Genetic Interaction with SGD:GEM1, SGD:YPT11, IMP: Inferred from Mutant Phenotype Assigned on 2008-06-05	manually curated	Frederick RL, et al.  (2008) Multiple pathways influence mitochondrial inheritance in budding yeast. Genetics 178(2):825-37	SGD
MYO2/YOR326W	IGI: Inferred from Genetic Interaction with SGD:YPT11, IMP: Inferred from Mutant Phenotype Assigned on 2006-10-19	manually curated	Itoh T, et al.  (2002) Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae. Mol Cell Biol 22(22):7744-57	SGD
	IGI: Inferred from Genetic Interaction with SGD:MMR1, IPI: Inferred from Physical Interaction with SGD:MMR1 Assigned on 2006-10-19	manually curated	Itoh T, et al.  (2004) Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast. EMBO J 23(13):2520-30	SGD
NAT3/YPR131C	IGI: Inferred from Genetic Interaction with SGD:MDM20, IMP: Inferred from Mutant Phenotype Assigned on 2005-06-15	manually curated	Singer JM and Shaw JM  (2003) Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proc Natl Acad Sci U S A 100(13):7644-9	SGD
NUM1/YDR150W	IGI: Inferred from Genetic Interaction with SGD:DNM1 Assigned on 2007-03-19	manually curated	Cerveny KL, et al.  (2007) Yeast mitochondrial division and distribution require the cortical num1 protein. Dev Cell 12(3):363-75	SGD
PHB1/YGR132C	IMP: Inferred from Mutant Phenotype Assigned on 2008-02-04	manually curated	Piper PW, et al.  (2002) The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell 1(2):149-57	SGD
PHB2/YGR231C	IMP: Inferred from Mutant Phenotype Assigned on 2008-02-04	manually curated	Piper PW, et al.  (2002) The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell 1(2):149-57	SGD
PTC1/YDL006W	IMP: Inferred from Mutant Phenotype Assigned on 2002-12-02	manually curated	Roeder AD, et al.  (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 9(4):917-30	SGD
TPM1/YNL079C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
TPM2/YIL138C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
YPT11/YNL304W	IGI: Inferred from Genetic Interaction Assigned on 2002-12-12	manually curated	Itoh T, et al.  (2002) Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae. Mol Cell Biol 22(22):7744-57	SGD
	IGI: Inferred from Genetic Interaction with SGD:MMR1, SGD:GEM1, IMP: Inferred from Mutant Phenotype Assigned on 2008-06-05	manually curated	Frederick RL, et al.  (2008) Multiple pathways influence mitochondrial inheritance in budding yeast. Genetics 178(2):825-37	SGD

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