GO term: kinetochore 
Ontology: Cellular Component (GO:0000776)
Definition: A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
View Ontology:
(graph) | 
(text)
Definition: A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
kinetochore (48 genes)
or to its variants containing one or more
qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | colocalizes_with: kinetochore | 1 |
| kinetochore | 21 | |
| High-throughput | none | none |
| Computational (download data) | kinetochore | 40 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
kinetochore or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| colocalizes_with: kinetochore 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| SPT4/YGR063C | IDA: Inferred from Direct Assay Assigned on 2012-02-24 |
manually curated | Crotti LB and Basrai MA (2004) Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae. EMBO J 23(8):1804-14 |
SGD |
| kinetochore 48 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AME1/YBR211C | IDA: Inferred from Direct Assay Assigned on 2003-12-30 |
manually curated | De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| ASK1/YKL052C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BIK1/YCL029C | IDA: Inferred from Direct Assay Assigned on 2004-09-22 |
manually curated | Lin H, et al. (2001) Polyploids require Bik1 for kinetochore-microtubule attachment. J Cell Biol 155(7):1173-84 |
SGD |
| BUB1/YGR188C | IDA: Inferred from Direct Assay Assigned on 2003-07-25 |
manually curated | Kitagawa K, et al. (2003) Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint. Mol Cell 11(5):1201-13 |
SGD |
| CBF1/YJR060W | IPI: Inferred from Physical Interaction with SGD:CBF2, SGD:CEP3, SGD:CTF13, SGD:SKP1 Assigned on 2011-08-22 |
manually curated | Hemmerich P, et al. (2000) Interaction of yeast kinetochore proteins with centromere-protein/transcription factor Cbf1. Proc Natl Acad Sci U S A 97(23):12583-8 |
SGD |
| CDC23/YHR166C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CHL4/YDR254W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CNN1/YFR046C | IDA: Inferred from Direct Assay Assigned on 2005-05-02 |
manually curated | De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CRM1/YGR218W | IDA: Inferred from Direct Assay Assigned on 2009-01-27 |
manually curated | Scott RJ, et al. (2009) The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast. J Cell Biol 184(1):21-9 |
SGD |
| CSE4/YKL049C | IGI: Inferred from Genetic Interaction Assigned on 2004-09-24 |
manually curated | Chen Y, et al. (2000) The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain. Mol Cell Biol 20(18):7037-48 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CTF19/YPL018W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CTF3/YLR381W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DAD1/YDR016C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DAD2/YKR083C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DAD3/YBR233W-A | IDA: Inferred from Direct Assay Assigned on 2003-04-23 |
manually curated | Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| DAD4/YDR320C-A | IDA: Inferred from Direct Assay Assigned on 2003-04-23 |
manually curated | Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 |
SGD |
| IPI: Inferred from Physical Interaction Assigned on 2005-03-28 |
manually curated | Li JM, et al. (2005) Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association. Mol Cell Biol 25(2):767-78 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| DAM1/YGR113W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DSN1/YIR010W | IDA: Inferred from Direct Assay Assigned on 2003-12-30 |
manually curated | Scharfenberger M, et al. (2003) Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex. EMBO J 22(24):6584-97 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| DUO1/YGL061C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| HSK3/YKL138C-A | IPI: Inferred from Physical Interaction Assigned on 2005-03-28 |
manually curated | Li JM, et al. (2005) Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association. Mol Cell Biol 25(2):767-78 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| IML3/YBR107C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| IPL1/YPL209C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| KRE28/YDR532C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MAD1/YGL086W | IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2009-01-27 |
manually curated | Scott RJ, et al. (2009) The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast. J Cell Biol 184(1):21-9 |
SGD |
| MCM16/YPR046W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MCM21/YDR318W | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MCM22/YJR135C | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MTW1/YAL034W-A | IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| NKP1/YDR383C | IDA: Inferred from Direct Assay Assigned on 2003-11-05 |
manually curated | Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| NKP2/YLR315W | IDA: Inferred from Direct Assay Assigned on 2003-11-05 |
manually curated | Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0995 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
