This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2002-07-08    Molecular Function | Biological Process | Cellular Component

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
snRNA binding	IPI: Inferred from Physical Interaction with SGD:SNR6 Assigned on 2009-11-03	Siliciano PG, et al.  (1987) An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA. Cell 50(4):585-92	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
mRNA splicing, via spliceosome	TAS: Traceable Author Statement Assigned on 2002-07-08	Hu J, et al.  (1995) Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains. Mol Cell Biol 15(3):1274-85	SGD

Manually curated Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
spliceosomal complex	IDA: Inferred from Direct Assay Assigned on 2002-07-08	Cheng SC and Abelson J  (1987) Spliceosome assembly in yeast. Genes Dev 1(9):1014-27	SGD
U4/U6 x U5 tri-snRNP complex	IDA: Inferred from Direct Assay Assigned on 2005-10-03	Gottschalk A, et al.  (1999) Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J 18(16):4535-48	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-02-19	Stevens SW and Abelson J  (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

There are no High-throughput annotations for SNR14

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

There are no Computational annotations for SNR14

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).