This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2010-06-21    Molecular Function | Biological Process

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
maltose alpha-glucosidase activity	IDA: Inferred from Direct Assay Assigned on 2010-06-21	Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903	SGD
sucrose alpha-glucosidase activity	IDA: Inferred from Direct Assay Assigned on 2010-06-21	Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
maltose catabolic process	IGI: Inferred from Genetic Interaction Assigned on 2010-06-21	Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903	SGD
sucrose catabolic process	IGI: Inferred from Genetic Interaction Assigned on 2010-06-21	Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

Cellular Component

High-throughput Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
plasma membrane	IDA: Inferred from Direct Assay Assigned on 2009-04-29	Delom F, et al.  (2006) The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Proteomics 6(10):3029-39	SGD

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

Molecular Function | Biological Process

Computational Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
alpha-glucosidase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.2.1.20 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
catalytic activity	IEA: Inferred from Electronic Annotation with EBI:IPR006589, EBI:IPR015902, EBI:IPR013781, EBI:IPR006047 Last updated 2013-03-02	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
cation binding	IEA: Inferred from Electronic Annotation with EBI:IPR006589, EBI:IPR006047 Last updated 2013-03-02	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
hydrolase activity	IEA: Inferred from Electronic Annotation with EBI:KW-0378 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
hydrolase activity, acting on glycosyl bonds	IEA: Inferred from Electronic Annotation with EBI:KW-0326 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
maltose alpha-glucosidase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.2.1.20 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB

Computational Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
carbohydrate metabolic process	IEA: Inferred from Electronic Annotation with EBI:IPR006589, EBI:IPR013781, EBI:IPR006047 Last updated 2013-03-02	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
maltose metabolic process	IEA: Inferred from Electronic Annotation with EBI:KW-0462 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
metabolic process	IEA: Inferred from Electronic Annotation with EBI:KW-0326 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).