This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2013-02-27    Molecular Function | Biological Process | Cellular Component

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
cell adhesion molecule binding	IDA: Inferred from Direct Assay Assigned on 2013-02-27	Cappellaro C, et al.  (1994) Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and alpha-agglutinin. EMBO J 13(20):4737-44	SGD
	IDA: Inferred from Direct Assay Assigned on 2013-02-27	Zhao H, et al.  (2001) Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules. J Bacteriol 183(9):2874-80	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
agglutination involved in conjugation with cellular fusion	IDA: Inferred from Direct Assay Assigned on 2013-02-27	Cappellaro C, et al.  (1991) Saccharomyces cerevisiae a- and alpha-agglutinin: characterization of their molecular interaction. EMBO J 10(13):4081-8	SGD

Manually curated Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
fungal-type cell wall	IDA: Inferred from Direct Assay Assigned on 2013-02-27	Cappellaro C, et al.  (1991) Saccharomyces cerevisiae a- and alpha-agglutinin: characterization of their molecular interaction. EMBO J 10(13):4081-8	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

There are no High-throughput annotations for AGA2

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

Biological Process

Computational Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
cell adhesion	IEA: Inferred from Electronic Annotation with EBI:KW-0130 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).