This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2010-05-11    Molecular Function | Biological Process | Cellular Component

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
inositol monophosphate 1-phosphatase activity	ISA: Inferred from Sequence Alignment with EBI:P0ADG4 Assigned on 2010-05-11 IDA: Inferred from Direct Assay Assigned on 2003-03-25	Lopez F, et al.  (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64	SGD
	IGI: Inferred from Genetic Interaction with SGD:INM1 Assigned on 2010-05-11 IMP: Inferred from Mutant Phenotype Assigned on 2010-05-11	Navarro-Avino JP, et al.  (2003) Yeast inositol mono- and trisphosphate levels are modulated by inositol monophosphatase activity and nutrients. Biochem Biophys Res Commun 302(1):41-5	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
inositol phosphate dephosphorylation	IDA: Inferred from Direct Assay Assigned on 2005-03-31	Lopez F, et al.  (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64	SGD
	IGI: Inferred from Genetic Interaction with SGD:INM1 Assigned on 2010-05-11 IMP: Inferred from Mutant Phenotype Assigned on 2010-05-11	Navarro-Avino JP, et al.  (2003) Yeast inositol mono- and trisphosphate levels are modulated by inositol monophosphatase activity and nutrients. Biochem Biophys Res Commun 302(1):41-5	SGD

Manually curated Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
cellular_component unknown	ND: No Biological Data Available Assigned on 2003-03-25	SGD  (2002) Use of the ND evidence code for Gene Ontology (GO) terms in SGD ()	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

There are no High-throughput annotations for INM2

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

Molecular Function | Biological Process

Computational Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
hydrolase activity	IEA: Inferred from Electronic Annotation with EBI:KW-0378 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
inositol monophosphate 1-phosphatase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.1.3.25 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
inositol monophosphate 3-phosphatase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.1.3.25 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
inositol monophosphate 4-phosphatase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.1.3.25 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
inositol monophosphate phosphatase activity	IEA: Inferred from Electronic Annotation with IUBMB:3.1.3.25 Last updated 2013-03-02	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
metal ion binding	IEA: Inferred from Electronic Annotation with EBI:KW-0479 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

Computational Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
inositol biosynthetic process	IEA: Inferred from Electronic Annotation with UniPathway:UPA00823 Last updated 2013-03-02	UniProt-GOA  (2012) Gene Ontology annotation based on UniPathway vocabulary mapping.	UniPathway
phosphatidylinositol phosphorylation	IEA: Inferred from Electronic Annotation with EBI:IPR020550, EBI:IPR000760 Last updated 2013-03-02	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).