This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2001-01-18    Molecular Function | Biological Process | Cellular Component

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
phosphatidic acid binding	IDA: Inferred from Direct Assay Assigned on 2009-05-15	Fernandez-Murray JP and McMaster CR  (2006) Identification of novel phospholipid binding proteins in Saccharomyces cerevisiae. FEBS Lett 580(1):82-6	SGD
phosphatidylinositol-3,5-bisphosphate binding	IDA: Inferred from Direct Assay Assigned on 2009-05-15	Fernandez-Murray JP and McMaster CR  (2006) Identification of novel phospholipid binding proteins in Saccharomyces cerevisiae. FEBS Lett 580(1):82-6	SGD
phosphatidylinositol-3-phosphate binding	IDA: Inferred from Direct Assay Assigned on 2009-05-15	Fernandez-Murray JP and McMaster CR  (2006) Identification of novel phospholipid binding proteins in Saccharomyces cerevisiae. FEBS Lett 580(1):82-6	SGD
phosphatidylinositol-4-phosphate binding	IDA: Inferred from Direct Assay Assigned on 2009-05-15	Fernandez-Murray JP and McMaster CR  (2006) Identification of novel phospholipid binding proteins in Saccharomyces cerevisiae. FEBS Lett 580(1):82-6	SGD
unfolded protein binding	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	George R, et al.  (1998) The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo. Proc Natl Acad Sci U S A 95(5):2296-301	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
'de novo' cotranslational protein folding	IPI: Inferred from Physical Interaction Assigned on 2001-01-18	Reimann B, et al.  (1999) Initial characterization of the nascent polypeptide-associated complex in yeast. Yeast 15(5):397-407	SGD

Manually curated Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
nascent polypeptide-associated complex	IDA: Inferred from Direct Assay Assigned on 2001-01-18	Reimann B, et al.  (1999) Initial characterization of the nascent polypeptide-associated complex in yeast. Yeast 15(5):397-407	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

There are no High-throughput annotations for EGD2

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

Biological Process | Cellular Component

Computational Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
protein transport	IEA: Inferred from Electronic Annotation with EBI:KW-0653 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
transport	IEA: Inferred from Electronic Annotation with EBI:KW-0813 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

Computational Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
cytoplasm	IEA: Inferred from Electronic Annotation with EBI:SL-0086 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:KW-0963 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
nucleus	IEA: Inferred from Electronic Annotation with EBI:SL-0191 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:KW-0539 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).