This page displays GO annotations in different sections according to the annotation method used to add that annotation to SGD.

Last Reviewed on: 2012-03-27    Molecular Function | Biological Process | Cellular Component

Manually curated Molecular Function
Annotation(s)	Evidence	Reference(s)	Assigned By
methylated histone residue binding	IDA: Inferred from Direct Assay Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD
RNA polymerase II transcription factor recruiting transcription factor activity	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD

Manually curated Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
cellular protein complex localization	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD
cellular protein localization	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-27	Shukla A, et al.  (2012) Sgf29p facilitates the recruitment of TATA box binding protein but does not alter SAGA's global structural integrity in vivo. Biochemistry 51(2):706-14	SGD
histone H3-K14 acetylation	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD
histone H3-K18 acetylation	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD
histone H3-K9 acetylation	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD
positive regulation of transcription from RNA polymerase II promoter	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-25	Bian C, et al.  (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J ()	SGD

Manually curated Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
Ada2/Gcn5/Ada3 transcription activator complex	IMP: Inferred from Mutant Phenotype Assigned on 2011-07-28 IPI: Inferred from Physical Interaction with SGD:GCN5, SGD:NGG1, SGD:ADA2 Assigned on 2011-07-28	Lee KK, et al.  (2011) Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Mol Syst Biol 7():503	SGD
SAGA complex	IDA: Inferred from Direct Assay Assigned on 2002-09-25	Sanders SL, et al.  (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38	SGD

* Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all Manually curated GO annotations for accuracy and completeness. The "Last Reviewed on:" date at the top of this section indicates when these annotations were last reviewed.

There are no High-throughput annotations for SGF29

** GO annotations from High-throughput experiments are made based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO Annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned in all three aspects of the Gene Ontologies.

Biological Process | Cellular Component

Computational Biological Process
Annotation(s)	Evidence	Reference(s)	Assigned By
chromatin modification	IEA: Inferred from Electronic Annotation with EBI:KW-0156 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
regulation of transcription, DNA-dependent	IEA: Inferred from Electronic Annotation with EBI:KW-0805 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
transcription, DNA-dependent	IEA: Inferred from Electronic Annotation with EBI:KW-0804 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

Computational Cellular Component
Annotation(s)	Evidence	Reference(s)	Assigned By
nucleus	IEA: Inferred from Electronic Annotation with EBI:SL-0191 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:KW-0539 Last updated 2013-03-02	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

*** Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).