• γ-tubulin and α-tubulin of the mitotic spindle.
    Image courtesy of Nádia Maria Sampaio, Rhesa Ledbetter and Melinda Borrie, Yeast Genetics and Genomics Course, Cold Spring Harbor Laboratory
  • Natural isolates of S. cerevisiae form complex mats on low-agar media.
    Image courtesy of Elyse A. Hope and Dr. Maitreya J. Dunham, University of Washington
  • slideshow24-new
    Floccule of yeast rho0 cells expressing PTS1-GFP as a peroxisomal marker, stained with calcofluor white.
    Image courtesy of Dr. Jakob Vowinckel, University of Cambridge
  • Colombo S and Martegani E
    Localization of active Ras in a wild type strain
    Image courtesy of S. Colombo and E. Martegani, University Milano Bicocca
  • Sectored Colonies
    Sectored colonies showing loss of silencing at the HML locus
    Image courtesy of Anne Dodson, UC Berkeley
  • Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Image courtesy of Dan Gottschling Ph.D., Fred Hutchinson Cancer Research Center
  • Lipid droplets in fld1 mutant images by CARS
    Lipid droplets in fld1 mutant images by CARS
    Image courtesy of Heimo Wolinski, Ph.D. and Sepp D. Kohlwein, Ph.D., University of Graz, Austria
  • Fpr3p accumulation in the nucleolus of S. cerevisiae
    Fpr3p accumulation in the nucleolus of S. cerevisiae
    Image courtesy of Amy MacQueen, Ph.D., Wesleyan University
    anti-Fpr3 antibody courtesy of Jeremy Thorner, Ph.D., UC Berkeley
  • San1 strain visualized with FUN and calcofluor white
    San1 strain visualized with FUN and calcofluor white
    Image courtesy of the Bruschi lab, ICGEB, Trieste, Italy
  • Single MDN1 mRNAs detected by FISH
    Single MDN1 mRNAs detected by FISH
    Image courtesy of the Zenklusen Lab, Université de Montréal
  • Localization of Ace2-GFP to daughter cell nuclei
    Localization of Ace2-GFP to daughter cell nuclei
    Image courtesy of Eric Weiss, Ph.D. Northwestern University

About SGD

The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.

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New & Noteworthy

  • Mother Yeast Keeps Daughters Tidy

    12/18/2014

    Yeast need translation and organelle tethering to sequester misfolded proteins away from the cytoplasm: Sometimes parents feel like they’re constantly nagging their kids to clean things up. Eventually, some parents just give in and do it themselves. It turns out that yeast cells aren’t all that different. And it is even more important for cells to clean up their cellular trash than it is for that sullen teenager. If trash like misfolded or damaged proteins is not... Read...
  • New Protein Modification and Abundance Data in YeastMine

    12/17/2014

    Have you ever wondered what’s happening to your favorite protein as it’s hanging out in the cell? SGD’s advanced search tool, YeastMine, now includes four new templates that can be used to find protein modification and abundance data. The Gene -> Protein Modifications template retrieves phosphorylation, ubiquitination, succinylation, acetylation and methylation data, currently curated from the following 11 publications: Peng et al. 2003, Hitchcock et al. 2003, Seyfried et al. 2008, Vogtle et... Read...
  • Telomerator is the Chromosomal Terminator

    12/10/2014

    A simple tool for adding telomeres to linear DNA: First there was the Terminator. Now, in a new study published in PNAS by Mitchell and Boeke, we have the telomerator. Instead of being a homicidal robot from the future bent on killing Sarah Connor, the telomerator is a tool that lets scientists easily turn circular DNA into stable chromosomes in the yeast Saccharomyces cerevisiae. While less splashy, this bit of synthetic biology is definitely cool in its... Read...
  • New Alternative Reference Genomes

    12/08/2014

    At SGD, we are expanding our scope to provide annotation and comparative analyses of all major budding yeast strains, and are making progress in our move toward providing multiple reference genomes. To this end, the following new S. cerevisiae genomes have been incorporated into SGD as “Alternative References”: CEN.PK, D273-10B, FL100, JK9-3d, RM11-1a, SEY6210, SK1, Sigma1278b, W303, X2180-1A, Y55. These genomes are accessible via Sequence, Strain, and Contig pages, and are the genomes for which... Read...

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