• γ-tubulin and α-tubulin of the mitotic spindle.
    Image courtesy of Nádia Maria Sampaio, Rhesa Ledbetter and Melinda Borrie, Yeast Genetics and Genomics Course, Cold Spring Harbor Laboratory
  • Natural isolates of S. cerevisiae form complex mats on low-agar media.
    Image courtesy of Elyse A. Hope and Dr. Maitreya J. Dunham, University of Washington
  • slideshow24-new
    Floccule of yeast rho0 cells expressing PTS1-GFP as a peroxisomal marker, stained with calcofluor white.
    Image courtesy of Dr. Jakob Vowinckel, University of Cambridge
  • Colombo S and Martegani E
    Localization of active Ras in a wild type strain
    Image courtesy of S. Colombo and E. Martegani, University Milano Bicocca
  • Sectored Colonies
    Sectored colonies showing loss of silencing at the HML locus
    Image courtesy of Anne Dodson, UC Berkeley
  • Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Image courtesy of Dan Gottschling Ph.D., Fred Hutchinson Cancer Research Center
  • Lipid droplets in fld1 mutant images by CARS
    Lipid droplets in fld1 mutant images by CARS
    Image courtesy of Heimo Wolinski, Ph.D. and Sepp D. Kohlwein, Ph.D., University of Graz, Austria
  • Fpr3p accumulation in the nucleolus of S. cerevisiae
    Fpr3p accumulation in the nucleolus of S. cerevisiae
    Image courtesy of Amy MacQueen, Ph.D., Wesleyan University
    anti-Fpr3 antibody courtesy of Jeremy Thorner, Ph.D., UC Berkeley
  • San1 strain visualized with FUN and calcofluor white
    San1 strain visualized with FUN and calcofluor white
    Image courtesy of the Bruschi lab, ICGEB, Trieste, Italy
  • Single MDN1 mRNAs detected by FISH
    Single MDN1 mRNAs detected by FISH
    Image courtesy of the Zenklusen Lab, Université de Montréal
  • Localization of Ace2-GFP to daughter cell nuclei
    Localization of Ace2-GFP to daughter cell nuclei
    Image courtesy of Eric Weiss, Ph.D. Northwestern University

About SGD

The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.

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New & Noteworthy

  • RNase P, Unmasked

    08/28/2014

    Masks for a masquerade party come in a dazzling array of shapes and sizes.  And yet they all pretty much serve the same purpose — they hide the identity of the wearer. Biology sometimes has its own dazzling array of cellular machines all doing the same thing.  One of the best examples of this is RNase P.   This enzyme trims tRNA precursors into mature tRNAs and has pretty much been around in one form or another... Read...
  • New Sequence, Chromosome, and Contig pages

    08/25/2014

    New Sequence pages are now available in SGD for virtually every yeast gene (e.g., HMRA1 Sequence page), and include genomic sequence annotations for the Reference Strain S288C, as well as several Alternative Reference Genomes from strains such as CEN.PK, RM11-1a, Sigma1278b, and W303 (more Alternative References coming soon). Each page includes an Overview section containing descriptive information, maps depicting genomic context in Reference Strain S288C (as shown below) and Alternative Reference strains, as well... Read...
  • Special Delivery for Cytotoxic Proteins

    08/21/2014

    Say you want to send a letter to your friend on the other side of the country. First off you’ll need to put the right address and postage on the envelope. Then you’ll need the U.S. Postal Service (USPS) to take your letter and deliver it to the right person. The stamp tells the USPS to deliver the letter, and the address indicates where it should be delivered (unimpeded by snow nor rain... Read...
  • Pinpointing Peroxisomes

    08/14/2014

    One way to think about the cell is that organelles float around in it like those globs in a lava lamp.  This is obviously a simplification, but it’s also true that organelles aren’t locked into place.  As usual, the real picture lies somewhere in between these two extremes. What we know about the architecture of the cell has mostly been discovered using classical cell biology and genetic techniques. But in a paper published in Molecular BioSystems,... Read...

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